Opinion on the re-evaluation of mono- and ...
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Article dans une revue scientifique: Article original
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Title :
Opinion on the re-evaluation of mono- and diglycerides of fatty acids (E 471) as food additive in foods for infants below 16 weeks of age and follow-up of their re-evaluation as food additives for uses in foods for all population groups.
Author(s) :
Younes, M. [Auteur]
Aquilina, G. [Auteur]
Castle, L. [Auteur]
Engel, K. H. [Auteur]
Fowler, P. [Auteur]
Frutos Fernandez, M. J. [Auteur]
Fürst, P. [Auteur]
Gürtler, R. [Auteur]
Husøy, T. [Auteur]
Manco, M. [Auteur]
Mennes, W. [Auteur]
Moldeus, P. [Auteur]
Passamonti, S. [Auteur]
Shah, R. [Auteur]
Waalkens-Berendsen, I. [Auteur]
Wölfle, D. [Auteur]
Wright, M. [Auteur]
Dusemund, B. [Auteur]
Mortensen, A. [Auteur]
Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Barmaz, S. [Auteur]
Tard, A. [Auteur]
Vianello, G. [Auteur]
Gundert-Remy, U. [Auteur]
Aquilina, G. [Auteur]
Castle, L. [Auteur]
Engel, K. H. [Auteur]
Fowler, P. [Auteur]
Frutos Fernandez, M. J. [Auteur]
Fürst, P. [Auteur]
Gürtler, R. [Auteur]
Husøy, T. [Auteur]
Manco, M. [Auteur]
Mennes, W. [Auteur]
Moldeus, P. [Auteur]
Passamonti, S. [Auteur]
Shah, R. [Auteur]
Waalkens-Berendsen, I. [Auteur]
Wölfle, D. [Auteur]
Wright, M. [Auteur]
Dusemund, B. [Auteur]
Mortensen, A. [Auteur]
Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Barmaz, S. [Auteur]
Tard, A. [Auteur]
Vianello, G. [Auteur]
Gundert-Remy, U. [Auteur]
Journal title :
EFSA Journal
Abbreviated title :
EFSA J
Volume number :
19
Pages :
e06885
Publication date :
2021-11-24
ISSN :
1831-4732
English keyword(s) :
mono- and diglycerides of fatty acids
E 471
food additive
infants
E 471
food additive
infants
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Mono- and diglycerides of fatty acids (E 471) was re-evaluated in 2017 by the former EFSA Panel onFood Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, thePanel on Food Additives and ...
Show more >Mono- and diglycerides of fatty acids (E 471) was re-evaluated in 2017 by the former EFSA Panel onFood Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, thePanel on Food Additives and Flavouring was requested to assess mono- and diglycerides of fatty acids(E 471) for its use as food additive in food for infants below 16 weeks of age belonging to foodcategories 13.1.1 (Infant formulae) and 13.1.5.1 (Dietary foods for infants for special medical purposesand special formulae for infants). In addition, the FAF Panel was requested to address the issuesalready identified during the re-evaluation of the food additive in 2017 when used in food for thegeneral population. The Panel considered that there is no indication of adverse effects from theavailable animal studies at the highest dose tested and from the post marketing data. A comparisonwas made between the daily exposure to the sum of mono- and di-acylglycerols from breast milk andthat resulting from the use of E 471 in the infant formula. The Panel noted that the resultingexposures are in the same order of magnitude. Overall, the Panel concluded that there is no reason fora safety concern when E 471 used as food additive in FC 13.1.1 and 13.1.5.1 and according to theAnnex III to Regulation (EC) No 1333/2008. The risk assessment for toxic elements and impuritiesclearly indicated the need to lower the current maximum limits for arsenic, lead, cadmium and mercuryand to include limits for glycidyl esters, 3-monochloropropane diol and erucic acid in the EUspecifications of E 471Show less >
Show more >Mono- and diglycerides of fatty acids (E 471) was re-evaluated in 2017 by the former EFSA Panel onFood Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, thePanel on Food Additives and Flavouring was requested to assess mono- and diglycerides of fatty acids(E 471) for its use as food additive in food for infants below 16 weeks of age belonging to foodcategories 13.1.1 (Infant formulae) and 13.1.5.1 (Dietary foods for infants for special medical purposesand special formulae for infants). In addition, the FAF Panel was requested to address the issuesalready identified during the re-evaluation of the food additive in 2017 when used in food for thegeneral population. The Panel considered that there is no indication of adverse effects from theavailable animal studies at the highest dose tested and from the post marketing data. A comparisonwas made between the daily exposure to the sum of mono- and di-acylglycerols from breast milk andthat resulting from the use of E 471 in the infant formula. The Panel noted that the resultingexposures are in the same order of magnitude. Overall, the Panel concluded that there is no reason fora safety concern when E 471 used as food additive in FC 13.1.1 and 13.1.5.1 and according to theAnnex III to Regulation (EC) No 1333/2008. The risk assessment for toxic elements and impuritiesclearly indicated the need to lower the current maximum limits for arsenic, lead, cadmium and mercuryand to include limits for glycidyl esters, 3-monochloropropane diol and erucic acid in the EUspecifications of E 471Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Submission date :
2024-01-12T05:40:47Z
2024-02-28T16:12:13Z
2024-02-28T16:12:13Z
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