Title :

CONSENT

Author(s) :

Morisse, Pierre [Auteur]
Marchet, Camille []
Centre National de la Recherche Scientifique [CNRS]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Limasset, Antoine []
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Centre National de la Recherche Scientifique [CNRS]
Lecroq, Thierry []
Equipe Traitement de l'information en Biologie Santé [TIBS - LITIS]
Lefebvre, Arnaud []

HAL domain(s) :

Informatique [cs]/Bio-informatique [q-bio.QM]
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]

English abstract : [en]

CONSENT (Scalable long read self-correction and assembly polishing with multiple sequence alignment) is a self-correction method for long reads. It works by, first, computing overlaps between the long reads, in order to ...
Show more >CONSENT (Scalable long read self-correction and assembly polishing with multiple sequence alignment) is a self-correction method for long reads. It works by, first, computing overlaps between the long reads, in order to define an alignment pile (i.e. a set of overlapping reads used for correction) for each read. Each read's alignment pile is then further divided into smaller windows, that are corrected idependently. First, a multiple alignment strategy is used in order to compute consensus. Then, this consensus is further polished with a local de Bruijn graph, in order to get rid of the remaining errors. Additionally to error correction, CONSENT can also perform assembly polishing.Show less >

Language :

Anglais

Collections :

• Centre de Recherche en Informatique, Signal et Automatique de Lille (CRIStAL) - UMR 9189

Source :

Harvested from HAL