Title :

Large-scale phenotyping of 1,000 fungal strains for the degradation of non-natural, industrial compounds

Author(s) :

Sinaeve, Sébastien [Auteur]
Husson, Cécile [Auteur]
Antoine, Marie-Hélène [Auteur]
Welti, Stéphane [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Decock, Cony [Auteur]
Stevigny, Caroline [Auteur]
Faculté de Pharmacie [Bruxelles] [ULB]
Nortier, Joelle [Auteur]

Journal title :

Communications Biology

Pages :

MO346

Publisher :

Nature Publishing Group

Publication date :

2021-12

ISSN :

2399-3642

HAL domain(s) :

Sciences du Vivant [q-bio]
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Mycologie

English abstract : [en]

Abstract Fungal biotechnology is set to play a keystone role in the emerging bioeconomy, notably to address pollution issues arising from human activities. Because they preserve biological diversity, Biological Resource ...
Show more >Abstract Fungal biotechnology is set to play a keystone role in the emerging bioeconomy, notably to address pollution issues arising from human activities. Because they preserve biological diversity, Biological Resource Centres are considered as critical infrastructures to support the development of biotechnological solutions. Here, we report the first large-scale phenotyping of more than 1,000 fungal strains with evaluation of their growth and degradation potential towards five industrial, human-designed and recalcitrant compounds, including two synthetic dyes, two lignocellulose-derived compounds and a synthetic plastic polymer. We draw a functional map over the phylogenetic diversity of Basidiomycota and Ascomycota , to guide the selection of fungal taxa to be tested for dedicated biotechnological applications. We evidence a functional diversity at all taxonomic ranks, including between strains of a same species. Beyond demonstrating the tremendous potential of filamentous fungi, our results pave the avenue for further functional exploration to solve the ever-growing issue of ecosystems pollution.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515

Source :

Harvested from HAL

Submission date :

2025-02-26T09:07:51Z