Title :

Nickel-Catalyzed α-Allylation of Aldehydes and Tandem Aldol Condensation/Allylation Reaction with Allylic Alcohols

Author(s) :

Bernhard, Yann [Auteur]
Unité de Catalyse et Chimie du Solide - UMR 8181 [UCCS]
Thomson, Brodie [Auteur]
Ferey, Vincent [Auteur]
Sauthier, Mathieu [Auteur]
Unité de Catalyse et Chimie du Solide - UMR 8181 [UCCS]
Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181

Journal title :

Angewandte Chemie International Edition

Volume number :

56

Pages :

7460-7464

Publication date :

2017-05-03

HAL domain(s) :

Chimie/Catalyse

English abstract : [en]

An additive-free nickel-catalyzed α-allylation of aldehydes with allyl alcohol is reported. The reaction is promoted by 1 mol % of in situ formed nickel complex in methanol, and water is the sole by-product of the reaction. ...
Show more >An additive-free nickel-catalyzed α-allylation of aldehydes with allyl alcohol is reported. The reaction is promoted by 1 mol % of in situ formed nickel complex in methanol, and water is the sole by-product of the reaction. The experimental conditions allow the conversion of various α-branched aldehydes and α,β-unsaturated aldehydes as nucleophiles. The same catalyst and reaction conditions enabled a tandem aldol condensation of aldehyde/α-allylation reaction.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

ENSCL
CNRS
Centrale Lille
Univ. Artois
Université de Lille

Collections :

• Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181

Research team(s) :

Catalyse et synthèse éco-compatible (CASECO)

Submission date :

2019-09-25T14:05:33Z