Title :

Attitudes of community pharmacists to off-label prescribing of baclofen in northern france

Author(s) :

Auffret, Marine [Auteur]
Rolland, Benjamin [Auteur]
Caous, Anne-Sylvie [Auteur]
Deheul, Sylvie [Auteur]
Bene, Johana [Auteur]
Cottencin, Olivier [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Bordet, Regis [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Gautier, Sophie [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 [TCDV]

Journal title :

International journal of clinical pharmacy

Abbreviated title :

Int. J. Clin. Phar,.

Volume number :

37

Pages :

296-299

Publication date :

2015-04-01

ISSN :

2210-7703

English keyword(s) :

Community pharmacists
Drug dispensing
France
Off-label
Baclofen
Alcohol dependence
Mesh:GABA-B Receptor Agonists/therapeutic use
Mesh:Humans
Mesh:Off-Label Use*
Mesh:Pharmacists/psychology*
Mesh:Surveys and Questionnaires
Mesh:Baclofen/therapeutic use*
Mesh:Attitude of Health Personnel*
Mesh:Alcoholism/epidemiology
Mesh:Alcoholism/drug therapy*
Mesh:Community Pharmacy Services*
Mesh:France/epidemiology

HAL domain(s) :

Sciences du Vivant [q-bio]
Sciences cognitives

English abstract : [en]

BACKGROUND: Community pharmacists' liability is involved when they dispense off-label prescriptions (OLPs). However, their attitudes to off-label prescribing are little known, while in France off-label baclofen use for ...
Show more >BACKGROUND: Community pharmacists' liability is involved when they dispense off-label prescriptions (OLPs). However, their attitudes to off-label prescribing are little known, while in France off-label baclofen use for alcohol dependence is increasing. OBJECTIVE: To determine community pharmacists' attitudes to off-label prescribing of baclofen. METHODS: A postal questionnaire was sent to 219 community pharmacies in the Nord-Pas-de-Calais region, France, previously identified as delivering at least five boxes of oral baclofen monthly. The questionnaire examined whether pharmacists delivered baclofen for alcohol dependence, how pharmacists detected off-label prescribing of baclofen, who were the most frequent prescribers (general practitioners or specialists), and pharmacists' attitudes to OLPs. RESULTS: Eighty pharmacies responded (36.5 %). Detection criteria for OLPs were supra-threshold dose (77.3 %) and "off-label" written on prescription (52.5 %). General practitioners were the most frequent prescribers of off-label baclofen. Pharmacists were more likely to refuse to fill prescriptions not marked "off-label" (6.0 %) than correctly marked prescriptions (1.5 %). 85 % of respondents considered they lacked information on off-label use. CONCLUSIONS: Although community pharmacists felt they were poorly informed on off-label baclofen, the majority nevertheless delivered the drug. Since our survey, off-label baclofen prescribing has been strictly controlled in France. Pharmacists' current attitudes will need further evaluation.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T13:33:37Z
2019-11-28T07:32:40Z