F-18-fdg-pet patterns of surgical success ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
F-18-fdg-pet patterns of surgical success and failure in mesial temporal lobe epilepsy
Auteur(s) :
Chassoux, Francine [Auteur]
Artiges, Eric [Auteur]
Semah, Franck [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Laurent, Agathe [Auteur]
Landre, Elisabeth [Auteur]
Turak, Baris [Auteur]
Gervais, Philippe [Auteur]
Helal, Badia-Ourkia [Auteur]
Devaux, Bertrand [Auteur]
Artiges, Eric [Auteur]
Semah, Franck [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Laurent, Agathe [Auteur]
Landre, Elisabeth [Auteur]
Turak, Baris [Auteur]
Gervais, Philippe [Auteur]
Helal, Badia-Ourkia [Auteur]
Devaux, Bertrand [Auteur]
Titre de la revue :
Neurology
Nom court de la revue :
Neurology
Numéro :
88
Pagination :
1045-1053
Date de publication :
2017-03-14
ISSN :
0028-3878
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
OBJECTIVE: To search for [18
METHODS: We analyzed metabolic data with [18
RESULTS: With a mean follow-up of >6 years (range 2-14 years), 85% of patients achieved a class I outcome, including 45% in class IA. Class IA outcome ...
Lire la suite >OBJECTIVE: To search for [18 METHODS: We analyzed metabolic data with [18 RESULTS: With a mean follow-up of >6 years (range 2-14 years), 85% of patients achieved a class I outcome, including 45% in class IA. Class IA outcome was associated with a focal anteromesial temporal hypometabolism, whereas non-IA outcome correlated with extratemporal metabolic changes that differed according to the lateralization: ipsilateral mesial frontal and perisylvian hypometabolism in right HS and contralateral fronto-insular hypometabolism and posterior white matter hypermetabolism in left HS. Suboptimal outcome presented a metabolic pattern similar to the best outcome but with a larger involvement of extratemporal areas, including the contralateral side in left HS. Failure was characterized by a mild temporal involvement sparing the hippocampus and relatively high extratemporal hypometabolism on both sides. These findings were concordant with electroclinical features reflecting the organization of the epileptogenic zone but were independent of the structural abnormalities detected on MRI. CONCLUSIONS: [18Lire moins >
Lire la suite >OBJECTIVE: To search for [18 METHODS: We analyzed metabolic data with [18 RESULTS: With a mean follow-up of >6 years (range 2-14 years), 85% of patients achieved a class I outcome, including 45% in class IA. Class IA outcome was associated with a focal anteromesial temporal hypometabolism, whereas non-IA outcome correlated with extratemporal metabolic changes that differed according to the lateralization: ipsilateral mesial frontal and perisylvian hypometabolism in right HS and contralateral fronto-insular hypometabolism and posterior white matter hypermetabolism in left HS. Suboptimal outcome presented a metabolic pattern similar to the best outcome but with a larger involvement of extratemporal areas, including the contralateral side in left HS. Failure was characterized by a mild temporal involvement sparing the hippocampus and relatively high extratemporal hypometabolism on both sides. These findings were concordant with electroclinical features reflecting the organization of the epileptogenic zone but were independent of the structural abnormalities detected on MRI. CONCLUSIONS: [18Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T13:34:56Z