Title :

Prognostic significance of pulsatile tinnitus in cervical artery dissection

Author(s) :

Kellert, Lars [Auteur]
Kloss, Manja [Auteur]
Pezzini, Alessandro [Auteur]
Debette, Stéphanie [Auteur]
LEYS, Didier [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Caso, Valeria [Auteur]
Thijs, Vincent N. S. [Auteur]
Bersano, Anna [Auteur]
Touze, Emmanuel [Auteur]
Tatlisumak, Turgut [Auteur]
Traenka, Christopher [Auteur]
Lyrer, Philippe A. [Auteur]
Engelter, Stefan T. [Auteur]
Metso, Tiina M. [Auteur]
Grond-Ginsbach, Caspar [Auteur]

Journal title :

European journal of neurology

Abbreviated title :

Eur. J. Neurol.

Volume number :

23

Pages :

1183-1187

Publication date :

2016-07-01

ISSN :

1351-5101

English keyword(s) :

acute ischaemic stroke
cervical artery dissection
outcome
pulsatile tinnitus

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study ...
Show more >Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1. Sixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD. The presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T14:28:35Z