Enhanced antibacterial activity of carbon ...
Type de document :
Compte-rendu et recension critique d'ouvrage
Titre :
Enhanced antibacterial activity of carbon dots functionalized with ampicillin combined with visible light triggered photodynamic effects
Auteur(s) :
Jijie, Roxana [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Barras, Alexandre [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Bouckaert, Julie [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF]
Dumitrascu, Nicoleta [Auteur]
Szunerits, Sabine [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Boukherroub, Rabah [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Barras, Alexandre [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Bouckaert, Julie [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF]
Dumitrascu, Nicoleta [Auteur]
Szunerits, Sabine [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Boukherroub, Rabah [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
NanoBioInterfaces - IEMN [NBI - IEMN]
Titre de la revue :
Colloids and Surfaces B: Biointerfaces
Pagination :
347 - 354
Éditeur :
Elsevier
Date de publication :
2018-10
ISSN :
0927-7765
Mot(s)-clé(s) en anglais :
Carbon dots
Ampicillin
Bactericidal activity
Escherichia coli
PDT
Ampicillin
Bactericidal activity
Escherichia coli
PDT
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire
Chimie
Chimie/Matériaux
Chimie
Chimie/Matériaux
Résumé en anglais : [en]
In the last years, carbon-based nanomaterials have attracted considerable attention in a wide range of fields, particularly in biomedicine, owing to their remarkable photo-physical and chemical properties. In this study, ...
Lire la suite >In the last years, carbon-based nanomaterials have attracted considerable attention in a wide range of fields, particularly in biomedicine, owing to their remarkable photo-physical and chemical properties. In this study, we demonstrate that amine-terminated carbon dots (CDs-NH2) functionalized with ampicillin (AMP) offer a new perspective for antibacterial treatment. The amine-functionalized carbon dots were used as a carrier for immobilization and delivery of ampicillin (CDs-AMP) and as a visible light-triggered antibacterial material. Additionally, AMP immobilization on the CDs-NH2 surface improves its stability in solution as compared to free AMP. The AMP conjugated CDs platform combines the antibacterial function of AMP and conserves the intrinsic theranostic properties of CDs-NH2. Therefore, the AMP immobilized onto CDs-NH2 surface together with the generation of moderate quantities of reactive oxygen species under visible light illumination is very effective to inactivate the growth of Escherichia coli.Lire moins >
Lire la suite >In the last years, carbon-based nanomaterials have attracted considerable attention in a wide range of fields, particularly in biomedicine, owing to their remarkable photo-physical and chemical properties. In this study, we demonstrate that amine-terminated carbon dots (CDs-NH2) functionalized with ampicillin (AMP) offer a new perspective for antibacterial treatment. The amine-functionalized carbon dots were used as a carrier for immobilization and delivery of ampicillin (CDs-AMP) and as a visible light-triggered antibacterial material. Additionally, AMP immobilization on the CDs-NH2 surface improves its stability in solution as compared to free AMP. The AMP conjugated CDs platform combines the antibacterial function of AMP and conserves the intrinsic theranostic properties of CDs-NH2. Therefore, the AMP immobilized onto CDs-NH2 surface together with the generation of moderate quantities of reactive oxygen species under visible light illumination is very effective to inactivate the growth of Escherichia coli.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Projet Européen :
Source :
Fichiers
- https://hal.archives-ouvertes.fr/hal-01925065/document
- Accès libre
- Accéder au document
- https://hal.archives-ouvertes.fr/hal-01925065/document
- Accès libre
- Accéder au document
- https://hal.archives-ouvertes.fr/hal-01925065/document
- Accès libre
- Accéder au document
- document
- Accès libre
- Accéder au document
- Manuscript%20CDs_revised_clean%20copy%20%281%29.pdf
- Accès libre
- Accéder au document
- Manuscript%20CDs_revised_clean%20copy%20%281%29.pdf
- Accès libre
- Accéder au document