Title :

NRPS toolbox for the discovery of new nonribosomal peptides and synthetases

Author(s) :

Pupin, Maude [Auteur]
Laboratoire d'Informatique Fondamentale de Lille [LIFL]
Bioinformatics and Sequence Analysis [BONSAI]
Smaïl-Tabbone, Malika [Auteur]
Knowledge representation, reasonning [ORPAILLEUR]
Jacques, Philippe [Auteur]
Laboratoire des Procédés Biologiques Génie Enzymatique et Microbien [PROBIOGEM]
Devignes, Marie-Dominique [Auteur correspondant]
Knowledge representation, reasonning [ORPAILLEUR]
Leclere, Valerie [Auteur]
Laboratoire des Procédés Biologiques Génie Enzymatique et Microbien [PROBIOGEM]

Scientific editor(s) :

François Coste et Denis Tagu

Conference title :

Journées Ouvertes en Biologie, l'Informatique et les Mathématiques - JOBIM 2012

City :

Rennes

Country :

France

Start date of the conference :

2012-07-03

Publication date :

2012

English keyword(s) :

database
protein annotation
nonribosomal peptides
nonribosomal synthetase

HAL domain(s) :

Informatique [cs]/Bio-informatique [q-bio.QM]
Sciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]
Informatique [cs]/Base de données [cs.DB]

English abstract : [en]

Nonribosomal peptide synthetases are huge multi-enzymatic complexes synthesizing peptides, but not through the classical process of transcription and then translation. The synthetases are organised in modules, each one ...
Show more >Nonribosomal peptide synthetases are huge multi-enzymatic complexes synthesizing peptides, but not through the classical process of transcription and then translation. The synthetases are organised in modules, each one integrating an amino acid in the final peptide. The modules are divided in domains providing specialized activities. So, those enzymes are as diverse as their products. We present our toolbox designed to annotate them accurately and promising results obtained on some Burkholderia, Bacillus and Pseudomonas genomes.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Nationale

Popular science :

Non

Collections :

• Centre de Recherche en Informatique, Signal et Automatique de Lille (CRIStAL) - UMR 9189

Source :

Harvested from HAL