Title :

Kinetic of NO₂ uptake by Phleum pratense pollen: Chemical and allergenic implications

Author(s) :

Chassard, G. [Auteur]
Physicochimie des Processus de Combustion et de l’Atmosphère - UMR 8522 [PC2A]
Choël, Marie [Auteur]
Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 [LASIRE]
Gosselin, S. [Auteur]
Physicochimie des Processus de Combustion et de l’Atmosphère - UMR 8522 [PC2A]
Vorng, H. [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Petitprez, D. [Auteur]
Physicochimie des Processus de Combustion et de l’Atmosphère - UMR 8522 [PC2A]
Shahali, Y. [Auteur]
Laboratoire Colloïdes et Matériaux Divisés [LCMD]
Tsicopoulos, A. [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Visez, N. [Auteur correspondant]
Physicochimie des Processus de Combustion et de l’Atmosphère - UMR 8522 [PC2A]

Journal title :

Environment International

Pages :

107 - 113

Publisher :

Elsevier

Publication date :

2015

ISSN :

0160-4120

English keyword(s) :

Pollen allergy
Air pollution
Uptake coefficient
TH1/TH2 balance

HAL domain(s) :

Chimie/Chimie théorique et/ou physique

English abstract : [en]

<i>Phleum pratense</i> pollen was exposed to NO₂ in a reactor allowing a continuous analysis of NO₂ concentration by FTIR. The uptake coefficient of NO₂ on pollen was calculated postulating ...
Show more ><i>Phleum pratense</i> pollen was exposed to NO₂ in a reactor allowing a continuous analysis of NO₂ concentration by FTIR. The uptake coefficient of NO₂ on pollen was calculated postulating a first order kinetic reaction and a value of (1.1 ± 0.1) × 10⁻⁷ was determined. NO₂ uptake was faster when the pollen water content was increased and when the pollen was pre-treated with ozone. The effect of NO2 exposure on pollen allergic properties was investigated by quantifying Th2- and Th1-associated chemokines in a model of human dendritic cells. Cellular analysis clearly showed that cells exposed to fumigated pollen favored the production of chemokines known to promote Th2-cell responses. Altogether these data demonstrate that NO₂ uptake by pollen directly correlates with increased Th2 response in human cells, and are in favor of the involvement of NO₂ pollution in the increase of allergic diseases.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Non spécifiée

Popular science :

Non

Collections :

• Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017

Source :

Harvested from HAL