Title :

Reward anticipation in schizophrenia: A coordinate-based meta-analysis

Author(s) :

Leroy, Arnaud [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Amad, Ali [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Lille Neurosciences & Cognition - U 1172 [LilNCog]
D'hondt, Fabien [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Lille Neurosciences & Cognition - U 1172 [LilNCog]
Pins, Delphine [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Jaafari, Nematollah [Auteur]
Université de Poitiers
Thomas, Pierre [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Lille Neurosciences & Cognition - U 1172 [LilNCog]

Jardri, Renaud [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Lille Neurosciences & Cognition - U 1172 [LilNCog]

Journal title :

Schizophrenia Research

Abbreviated title :

Schizophrenia Research

Volume number :

218

Pages :

2-6

Publisher :

Elsevier BV

Publication date :

2020-04

Article status :

Publié

ISSN :

0920-9964

English keyword(s) :

Reward
Salience
Schizophrenia
Antipsychotics
fMRI
Meta-analysis

HAL domain(s) :

Sciences cognitives/Neurosciences
Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Psychiatrie et santé mentale

English abstract : [en]

Reward processing impairments have been linked with positive and negative symptoms of schizophrenia. Here, we performed a coordinate-based meta-analysis that combined eleven BOLD-fMRI studies comparing reward anticipation ...
Show more >Reward processing impairments have been linked with positive and negative symptoms of schizophrenia. Here, we performed a coordinate-based meta-analysis that combined eleven BOLD-fMRI studies comparing reward anticipation signals between schizophrenia patients and healthy controls. We observed a reduced difference in activation in schizophrenia patients within a frontal-striatal network. Meta-regressions revealed that this functional signature was linked to the severity of psychotic symptoms and persisted even after controlling for the dose of antipsychotic medications.Show less >

Peer reviewed article :

Oui

Audience :

Internationale

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Plasticity and Subjectivity (PSY)

Submission date :

2020-10-03T08:55:15Z
2020-10-03T17:01:27Z
2020-10-22T06:42:45Z
2020-11-13T14:51:24Z
2021-01-11T13:16:46Z