Isolated tricuspid valve surgery: impact ...
Type de document :
Compte-rendu et recension critique d'ouvrage
PMID :
Titre :
Isolated tricuspid valve surgery: impact of aetiology and clinical presentation on outcomes
Auteur(s) :
Dreyfus, Julien [Auteur correspondant]
Centre cardiologique du Nord [CCN]
Flagiello, Michele [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Bazire, Baptiste [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Eggenspieler, Florian [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Viau, Florence [Auteur]
Assistance Publique - Hôpitaux de Marseille [APHM]
Riant, Elisabeth [Auteur]
CHU Henri Mondor [Créteil]
Mbaki, Yannick [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Bohbot, Yohann [Auteur]
CHU Amiens-Picardie
Eyharts, Damien [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Sénage, Thomas [Auteur]
Centre Hospitalier Universitaire de Nantes [CHU Nantes]
MethodS in Patients-centered outcomes and HEalth ResEarch [SPHERE]
Dubrulle, Henri [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Nicol, Martin [Auteur]
Centre cardiologique du Nord [CCN]
Doguet, Fabien [Auteur]
CHU Rouen
Endothélium, valvulopathies et insuffisance cardiaque [EnVI]
Nguyen, Virginia [Auteur]
Centre cardiologique du Nord [CCN]
Coisne, Augustin [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Le Tourneau, Thierry [Auteur]
ITX - unité de recherche de l'institut du thorax [ITX]
Centre Hospitalier Universitaire de Nantes [CHU Nantes]
Lavie-Badie, Yoan [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Tribouilloy, Christophe [Auteur]
CHU Amiens-Picardie
Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 [MP3CV]
Donal, Erwan [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Tomasi, Jacques [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Habib, Gilbert [Auteur]
Assistance Publique - Hôpitaux de Marseille [APHM]
Microbes évolution phylogénie et infections [MEPHI]
Selton-Suty, Christine [Auteur]
Service de Cardiologie [CHRU Nancy]
Raffoul, Richard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Iung, Bernard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Obadia, J.-F. [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Messika-Zeitoun, David [Auteur correspondant]
University of Ottawa [Ottawa]
Centre cardiologique du Nord [CCN]
Flagiello, Michele [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Bazire, Baptiste [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Eggenspieler, Florian [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Viau, Florence [Auteur]
Assistance Publique - Hôpitaux de Marseille [APHM]
Riant, Elisabeth [Auteur]
CHU Henri Mondor [Créteil]
Mbaki, Yannick [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Bohbot, Yohann [Auteur]
CHU Amiens-Picardie
Eyharts, Damien [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Sénage, Thomas [Auteur]
Centre Hospitalier Universitaire de Nantes [CHU Nantes]
MethodS in Patients-centered outcomes and HEalth ResEarch [SPHERE]
Dubrulle, Henri [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Nicol, Martin [Auteur]
Centre cardiologique du Nord [CCN]
Doguet, Fabien [Auteur]
CHU Rouen
Endothélium, valvulopathies et insuffisance cardiaque [EnVI]
Nguyen, Virginia [Auteur]
Centre cardiologique du Nord [CCN]
Coisne, Augustin [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Le Tourneau, Thierry [Auteur]
ITX - unité de recherche de l'institut du thorax [ITX]
Centre Hospitalier Universitaire de Nantes [CHU Nantes]
Lavie-Badie, Yoan [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Tribouilloy, Christophe [Auteur]
CHU Amiens-Picardie
Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 [MP3CV]
Donal, Erwan [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Tomasi, Jacques [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Habib, Gilbert [Auteur]
Assistance Publique - Hôpitaux de Marseille [APHM]
Microbes évolution phylogénie et infections [MEPHI]
Selton-Suty, Christine [Auteur]
Service de Cardiologie [CHRU Nancy]
Raffoul, Richard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Iung, Bernard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Obadia, J.-F. [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Messika-Zeitoun, David [Auteur correspondant]
University of Ottawa [Ottawa]
Titre de la revue :
European Heart Journal
Pagination :
4304-4317
Éditeur :
Oxford University Press (OUP)
Date de publication :
2020-09-25
ISSN :
0195-668X
Mot(s)-clé(s) en anglais :
Outcome
Surgery
Tricuspid regurgitation
Surgery
Tricuspid regurgitation
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Ingénierie biomédicale
Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
Résumé en anglais : [en]
Aims: The aim of this study was to identify determinants of in-hospital and mid-term outcomes after isolated tricuspid valve surgery (ITVS) and more specifically the impact of tricuspid regurgitation (TR) mechanism and ...
Lire la suite >Aims: The aim of this study was to identify determinants of in-hospital and mid-term outcomes after isolated tricuspid valve surgery (ITVS) and more specifically the impact of tricuspid regurgitation (TR) mechanism and clinical presentation.Methods and results: Among 5661 consecutive adult patients who underwent a tricuspid valve (TV) surgery at 12 French tertiary centres in 2007-2017 collected from a mandatory administrative database, we identified 466 patients (8% of all tricuspid surgeries) who underwent an ITVS. Most patients presented with advanced disease [47% in New York Heart Association (NYHA) III/IV, 57% with right-sided heart failure (HF) signs]. Tricuspid regurgitation was functional in 49% (22% with prior left-sided heart valve surgery and 27% isolated) and organic in 51% (infective endocarditis in 31% and other causes in 20%). In-hospital mortality and major complications rates were 10% and 31%, respectively. Rates of survival and survival free of HF readmission were 75% and 62% at 5 years. Patients with functional TR incurred a worse in-hospital mortality than those with organic TR (14% vs. 6%, P = 0.004), but presentation was more severe. Independent determinants of outcomes were NYHA Class III/IV [odd ratios (OR) = 2.7 (1.2-6.1), P = 0.01], moderate/severe right ventricular dysfunction [OR = 2.6 (1.2-5.8), P = 0.02], lower prothrombin time [OR = 0.98 (0.96-0.99), P = 0.008], and with borderline statistical significance, right-sided HF signs [OR = 2.4 (0.9-6.5), P = 0.06] while TR mechanism was not [OR = 0.7 (0.3-1.8), P = 0.88].Conclusion: Isolated TV surgery was associated with high mortality and morbidity, both in hospital and during follow-up, predicted by the severity of the presentation but not by TR mechanism. Our results suggest that TV intervention should be performed earlier in the course of the disease.Lire moins >
Lire la suite >Aims: The aim of this study was to identify determinants of in-hospital and mid-term outcomes after isolated tricuspid valve surgery (ITVS) and more specifically the impact of tricuspid regurgitation (TR) mechanism and clinical presentation.Methods and results: Among 5661 consecutive adult patients who underwent a tricuspid valve (TV) surgery at 12 French tertiary centres in 2007-2017 collected from a mandatory administrative database, we identified 466 patients (8% of all tricuspid surgeries) who underwent an ITVS. Most patients presented with advanced disease [47% in New York Heart Association (NYHA) III/IV, 57% with right-sided heart failure (HF) signs]. Tricuspid regurgitation was functional in 49% (22% with prior left-sided heart valve surgery and 27% isolated) and organic in 51% (infective endocarditis in 31% and other causes in 20%). In-hospital mortality and major complications rates were 10% and 31%, respectively. Rates of survival and survival free of HF readmission were 75% and 62% at 5 years. Patients with functional TR incurred a worse in-hospital mortality than those with organic TR (14% vs. 6%, P = 0.004), but presentation was more severe. Independent determinants of outcomes were NYHA Class III/IV [odd ratios (OR) = 2.7 (1.2-6.1), P = 0.01], moderate/severe right ventricular dysfunction [OR = 2.6 (1.2-5.8), P = 0.02], lower prothrombin time [OR = 0.98 (0.96-0.99), P = 0.008], and with borderline statistical significance, right-sided HF signs [OR = 2.4 (0.9-6.5), P = 0.06] while TR mechanism was not [OR = 0.7 (0.3-1.8), P = 0.88].Conclusion: Isolated TV surgery was associated with high mortality and morbidity, both in hospital and during follow-up, predicted by the severity of the presentation but not by TR mechanism. Our results suggest that TV intervention should be performed earlier in the course of the disease.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Source :
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