Diagnostic value of bright spotty lesions ...
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Diagnostic value of bright spotty lesions on mri after a first episode of acute myelopathy
Author(s) :
Rabaste, Sylvain [Auteur]
Cobo-Calvo, Alvaro [Auteur]
Nistiriuc-Muntean, Veronica [Auteur]
Vukusic, Sandra [Auteur]
Marignier, Romain [Auteur]
Cotton, Francois [Auteur]
Cobo-Calvo, Alvaro [Auteur]
Nistiriuc-Muntean, Veronica [Auteur]
Vukusic, Sandra [Auteur]
Marignier, Romain [Auteur]
Cotton, Francois [Auteur]
Journal title :
Journal of neuroradiology. Journal de neuroradiologie
Abbreviated title :
J Neuroradiol
Publication date :
2020-05-12
ISSN :
0150-9861
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
OBJECTIVE: To determine the diagnostic value of bright spotty lesions (BSLs) for aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (NMOSDAQP4+AQP4+
METHODS: Retrospective study that included patients ...
Show more >OBJECTIVE: To determine the diagnostic value of bright spotty lesions (BSLs) for aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (NMOSDAQP4+AQP4+ METHODS: Retrospective study that included patients aged≥16 years, with a first acute spinal cord syndrome between 2005 and 2018 and abnormal spinal cord MRI with axial and sagittal T2 sequences. Patients with MRI findings consistent with compressive myelopathy were excluded. All spinal cord MRI were retrospectively evaluated for the presence of BSLs by 2 radiologists blinded to the diagnosis of acute myelopathy. RESULTS: A total of 82 patients were included; 15 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients (NMOSDAQP4+AQP4+AQP4+ CONCLUSIONS: After a first acute spinal cord syndrome, the presence of axial-BSLs on spinal cord MRI seems very specific for NMOSDAQP4+Show less >
Show more >OBJECTIVE: To determine the diagnostic value of bright spotty lesions (BSLs) for aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (NMOSDAQP4+AQP4+ METHODS: Retrospective study that included patients aged≥16 years, with a first acute spinal cord syndrome between 2005 and 2018 and abnormal spinal cord MRI with axial and sagittal T2 sequences. Patients with MRI findings consistent with compressive myelopathy were excluded. All spinal cord MRI were retrospectively evaluated for the presence of BSLs by 2 radiologists blinded to the diagnosis of acute myelopathy. RESULTS: A total of 82 patients were included; 15 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients (NMOSDAQP4+AQP4+AQP4+ CONCLUSIONS: After a first acute spinal cord syndrome, the presence of axial-BSLs on spinal cord MRI seems very specific for NMOSDAQP4+Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
Inserm
Université de Lille
Inserm
Université de Lille
Collections :
Research team(s) :
Neuroinflammation & Multiple Sclerosis (NEMESIS)
Submission date :
2021-06-23T11:41:14Z