A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications

Arscott, Steve; Gac, Séverine Le; Druon, Christian; Tabourier, Pierre; Rolando, Christian

Document type :

Compte-rendu et recension critique d'ouvrage

DOI :

10.1088/0960-1317/14/2/021

Title :

A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications

Author(s) :

Arscott, Steve [Auteur]

Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Gac, Séverine Le [Auteur]
Druon, Christian [Auteur]
Tabourier, Pierre [Auteur]
Rolando, Christian [Auteur]

Miniaturisation pour la Synthèse, l’Analyse et la Protéomique - UAR 3290 [MSAP]

Journal title :

Journal of Micromechanics and Microengineering

Pages :

310-316

Publisher :

IOP Publishing

Publication date :

2004-02-01

ISSN :

0960-1317

HAL domain(s) :

Sciences de l'ingénieur [physics]

English abstract : [en]

We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization-mass spectrometry (ESI-MS) applications. The fabrication of the micro-nibs relies on ...
Show more >We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization-mass spectrometry (ESI-MS) applications. The fabrication of the micro-nibs relies on micromachining techniques using the epoxy-based negative photoresist SU-8. A double exposure photolithographic process has been employed to form a nib in a membrane-like structure. The nibs contained a capillary slot measuring 20 µm at the tip end. The nib sources were successfully tested on an ion trap mass spectrometer using standard peptide samples at low concentrations, down to 1 µM. High voltage (HV) supply was achieved using platinum wire inserted in a liquid reservoir. A Taylor cone was clearly seen protruding from the nib tip and was determined by the dimensions of the capillary slot.Show less >

Language :

Anglais

Popular science :

Non

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