Oxygenated lanostane-type triterpenes profiling in laccate Ganoderma chemotaxonomy

Welti, Stephane; Moreau, Pierre-Arthur; Decock, C; Danel, Cecile; Duhal, Nathalie; Favel, A; Courtecuisse, Regis

Document type :

Article dans une revue scientifique: Article original

DOI :

10.1007/s11557-015-1066-7

Permalink :

http://hdl.handle.net/20.500.12210/4451

Title :

Oxygenated lanostane-type triterpenes profiling in laccate Ganoderma chemotaxonomy

Author(s) :

Welti, Stephane [Auteur]

Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Moreau, Pierre-Arthur [Auteur]

Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Decock, C [Auteur]
Université Catholique de Louvain = Catholic University of Louvain [UCL]
Danel, Cecile [Auteur]

Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Duhal, Nathalie [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Favel, A [Auteur]
Aix Marseille Université [AMU]
Courtecuisse, Regis [Auteur]

Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]

Journal title :

Mycological Progress

Abbreviated title :

Mycol. Prog.

Volume number :

Publication date :

2015

ISSN :

1617-416X

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Oxygenated lanostane-type triterpenes (OLTT), including ganoderic acids and lucidenic acids produced by fungi of the genus Ganoderma (Polyporales), are abundantly documented for their potential pharmacological value. In ...
Show more >Oxygenated lanostane-type triterpenes (OLTT), including ganoderic acids and lucidenic acids produced by fungi of the genus Ganoderma (Polyporales), are abundantly documented for their potential pharmacological value. In order to test the correlation between species identity and OLTT composition, methanolic extracts of seven laccate Ganoderma species were analyzed by liquid chromatography coupled to mass spectrometry. OLTT profiles of each species were compared to a phylogenetic reconstruction of Ganoderma based on ITS rDNA sequences. The results suggest a high specificity in OLTT composition in one of the phylogenetic lineages of Ganoderma that encompasses tropical species, when no OLTT compound was detected in other lineages (including the European G. lucidum and the Asian G. sinense). Within the OLTT-positive lineage, G. sichuanense, G. martinicense, and G. tuberculosum (Asian-tropicum clade) were characterized by a specific composition in ganoderic acids and G. curtisii by a variety of lucidenic acids. An unidentified OLTT was found in G. resinaceum, also equivocally positioned in phylogenetic analyses. These results confirm OLTT as a suitable taxonomic marker in a lineage of pharmacologically and economically valuable species. Correlations with phylogeny, and development of OLTT composition as a fingerprint tool for quality control, could be an issue to address next, based on a more complete species sampling.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille
Institut Pasteur de Lille

Collections :

Research team(s) :

Modélisation biopharmaceutique et pharmacocinétique

Submission date :

2019-02-26T17:11:51Z
2021-06-17T14:50:25Z
2022-11-30T09:13:44Z

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Version	Link	Modification date
3	20.500.12210/4451*	2022-11-30T08:29:24Z
2	20.500.12210/4451.2	2021-06-17T14:49:33Z
1	20.500.12210/4451.1	2019-02-26T17:11:51Z

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Oxygenated lanostane-type triterpenes ...

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