Title :

IL-7 Restores T Lymphocyte Immunometabolic Failure in Septic Shock Patients through mTOR Activation

Author(s) :

Venet, Fabienne [Auteur]
Demaret, Julie [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Blaise Benjamin, J [Auteur]
Rouget, Christelle [Auteur]
Girardot, Thibaut [Auteur]
Idealisoa, Estellie [Auteur]
Rimmele, Thomas [Auteur]
Mallet, Francois [Auteur]
Lepape, Alain [Auteur]
Textoris, Julien [Auteur]
Monneret, Guillaume [Auteur]

Journal title :

Journal of immunology

Abbreviated title :

J. Immunol.

Volume number :

199

Pages :

1606-1615

Publication date :

2017-09-01

ISSN :

0022-1767

Keyword(s) :

Mesh:Shock
Mesh:Septic/therapy
Mesh:T-Lymphocytes/immunology*
Mesh:Humans
Mesh:Glucose Transporter Type 1/metabolism
Mesh:Energy Metabolism/drug effects
Mesh:Cell Proliferation/drug effects
Mesh:Aged
Mesh:TOR Serine-Threonine Kinases/metabolism*
Mesh:Immunotherapy/methods*
Mesh:Aged
Mesh:80 and over
Mesh:Glucose/metabolism*
Mesh:Glucose Transporter Type 1/genetics
Mesh:Female
Mesh:Nuclear Magnetic Resonance
Mesh:Biomolecular
Mesh:Cells
Mesh:Cultured
Mesh:Sirolimus/pharmacology
Mesh:Middle Aged
Mesh:Interleukin-7/immunology*
Mesh:T-Lymphocytes/metabolism
Mesh:Oxidative Phosphorylation/drug effects
Mesh:Male
Mesh:Adenosine Triphosphate/metabolism
Mesh:Shock
Mesh:Septic/immunology*
Mesh:Interleukin-7/therapeutic use
Mesh:Glycolysis/drug effects

HAL domain(s) :

Sciences du Vivant [q-bio]

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Lille Inflammation Research International Center (LIRIC) - U995

Research team(s) :

Immunity, inflammation and fibrsis in auto and allo-reactivity

Submission date :

2019-03-01T14:26:33Z