Activity-dependent regulation of myelin ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Activity-dependent regulation of myelin maintenance in the adult rat.
Auteur(s) :
Canu, Marie-Helene [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Carnaud, Michèle [Auteur]
Institut du Fer à Moulin
Picquet, Florence [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - EA 7369
Goutebroze, Laurence [Auteur]
Institut du Fer à Moulin [IFM - Inserm U1270 - SU]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Carnaud, Michèle [Auteur]
Institut du Fer à Moulin
Picquet, Florence [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - EA 7369
Goutebroze, Laurence [Auteur]
Institut du Fer à Moulin [IFM - Inserm U1270 - SU]
Titre de la revue :
Brain research
Nom court de la revue :
Brain Res
Numéro :
1252
Pagination :
45-51
Date de publication :
2009-02-03
ISSN :
1872-6240
Mot(s)-clé(s) en anglais :
Animals
Axons
Hindlimb Suspension
Male
Microscopy, Fluorescence
Motor Activity
Myelin Sheath
Nerve Fibers, Myelinated
Neural Conduction
Neuronal Plasticity
Peripheral Nerves
Radial Nerve
Ranvier's Nodes
Rats
Rats, Wistar
Axons
Hindlimb Suspension
Male
Microscopy, Fluorescence
Motor Activity
Myelin Sheath
Nerve Fibers, Myelinated
Neural Conduction
Neuronal Plasticity
Peripheral Nerves
Radial Nerve
Ranvier's Nodes
Rats
Rats, Wistar
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Hindlimb unloading (HU) is known to induce changes in the neuromuscular system. However, no data describing the effects of HU on morphological characteristics of peripheral nerve have been reported so far. Therefore, we ...
Lire la suite >Hindlimb unloading (HU) is known to induce changes in the neuromuscular system. However, no data describing the effects of HU on morphological characteristics of peripheral nerve have been reported so far. Therefore, we used soleus and radial nerves obtained from control and rats submitted to 14 days of HU to study the consequences of a decrease (soleus) or an increase (radial) in neural activity on its morphology. The mean number of fibers was not changed after HU. The soleus nerve axon diameter was weakly affected after HU, whereas the myelin thickness was reduced. For the radial nerve, both axon and fiber diameter were increased, and the myelin thickness and internodal distance were higher in HU rats. These results suggest that regulation of myelin maintenance undergoes plastic mechanisms. Neural activity and/or neural pattern might be essential in the maintenance of myelin sheath in adults.Lire moins >
Lire la suite >Hindlimb unloading (HU) is known to induce changes in the neuromuscular system. However, no data describing the effects of HU on morphological characteristics of peripheral nerve have been reported so far. Therefore, we used soleus and radial nerves obtained from control and rats submitted to 14 days of HU to study the consequences of a decrease (soleus) or an increase (radial) in neural activity on its morphology. The mean number of fibers was not changed after HU. The soleus nerve axon diameter was weakly affected after HU, whereas the myelin thickness was reduced. For the radial nerve, both axon and fiber diameter were increased, and the myelin thickness and internodal distance were higher in HU rats. These results suggest that regulation of myelin maintenance undergoes plastic mechanisms. Neural activity and/or neural pattern might be essential in the maintenance of myelin sheath in adults.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
Univ. Artois
Univ. Littoral Côte d’Opale
Univ. Artois
Univ. Littoral Côte d’Opale
Équipe(s) de recherche :
Activité Physique, Muscle, Santé (APMS)
Date de dépôt :
2021-08-10T16:32:43Z
2021-09-01T09:02:47Z
2021-09-01T09:02:47Z
Fichiers
- Canu et al 2009.pdf
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