Dietary exposure to cadmium and health ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Dietary exposure to cadmium and health risk assessment in children - results of the french infant total diet study
Auteur(s) :
Jean, Julien [Auteur]
Sirot, Veronique [Auteur]
Hulin, Marion [Auteur]
Le Calvez, Emilie [Auteur]
Zinck, Julie [Auteur]
Noel, Laurent [Auteur]
Vasseur, Paule [Auteur]
Nesslany, Fabrice [Auteur]
Gorecki, Sebastien [Auteur]
Guerin, Thierry [Auteur]
Riviere, Gilles [Auteur]
Sirot, Veronique [Auteur]
Hulin, Marion [Auteur]
Le Calvez, Emilie [Auteur]
Zinck, Julie [Auteur]
Noel, Laurent [Auteur]
Vasseur, Paule [Auteur]
Nesslany, Fabrice [Auteur]
Gorecki, Sebastien [Auteur]
Guerin, Thierry [Auteur]
Riviere, Gilles [Auteur]
Titre de la revue :
Food and Chemical Toxicology
Nom court de la revue :
Food Chem. Toxicol.
Date de publication :
2018-03-23
ISSN :
1873-6351
Mot(s)-clé(s) :
Accumulation rate
Exposure assessment
Infant total diet study
Cadmium
Exposure assessment
Infant total diet study
Cadmium
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Besides specific occupational activities or smoking, food is the main route of cadmium exposure for the general population. In France a total diet study previously conducted for adults and children over 3 years old revealed ...
Lire la suite >Besides specific occupational activities or smoking, food is the main route of cadmium exposure for the general population. In France a total diet study previously conducted for adults and children over 3 years old revealed that health concerns due to Cd dietary exposure existed for both adults and children. This study showed that the Cd tolerable weekly intake, based on potential nephrotoxicity effects, is exceeded by a high proportion of children under 3 years old. Nephrotoxicity results from the accumulation of cadmium in the kidney and appears typically after long-term exposure (40-50 years). Despite the exceeding of the tolerable weekly intake observed during the first three years of childhood, due to low body weights compared to adults, the accumulation rate of cadmium is much lower during the whole childhood period (from 0 to 17 years of age) than during adulthood. These data suggest that dietary exposure to cadmium should be reduced for both children and adults to prevent health concerns associated with nephrotoxicity in later life. Moreover, recent literature suggests that Cd can induce other adverse health effects (especially endocrine disruption or neurotoxicity) that could be triggered at even lower doses than those triggering nephrotoxicity.Lire moins >
Lire la suite >Besides specific occupational activities or smoking, food is the main route of cadmium exposure for the general population. In France a total diet study previously conducted for adults and children over 3 years old revealed that health concerns due to Cd dietary exposure existed for both adults and children. This study showed that the Cd tolerable weekly intake, based on potential nephrotoxicity effects, is exceeded by a high proportion of children under 3 years old. Nephrotoxicity results from the accumulation of cadmium in the kidney and appears typically after long-term exposure (40-50 years). Despite the exceeding of the tolerable weekly intake observed during the first three years of childhood, due to low body weights compared to adults, the accumulation rate of cadmium is much lower during the whole childhood period (from 0 to 17 years of age) than during adulthood. These data suggest that dietary exposure to cadmium should be reduced for both children and adults to prevent health concerns associated with nephrotoxicity in later life. Moreover, recent literature suggests that Cd can induce other adverse health effects (especially endocrine disruption or neurotoxicity) that could be triggered at even lower doses than those triggering nephrotoxicity.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Institut Pasteur de Lille
Université de Lille
Institut Pasteur de Lille
Université de Lille
Collections :
Date de dépôt :
2022-02-02T10:23:34Z
2024-03-13T09:18:56Z
2024-03-13T09:18:56Z