Effect of lactobacillus reuteri on gingival ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Effect of lactobacillus reuteri on gingival inflammation and composition of the oral microbiota in patients undergoing treatment with fixed orthodontic appliances: study protocol of a randomized control trial
Auteur(s) :
Agossa, Kevimy [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Dubar, Marie [Auteur]
Lemaire, Gregoire [Auteur]
Blaizot, Alessandra [Auteur]
Catteau, Celine [Auteur]
Bocquet, Emmanuel [Auteur]
Nawrocki, Laurent [Auteur]
Boyer, Emile [Auteur]
Meuric, Vincent [Auteur]
Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Advanced Drug Delivery Systems (ADDS) - U1008
Dubar, Marie [Auteur]
Lemaire, Gregoire [Auteur]
Blaizot, Alessandra [Auteur]
Catteau, Celine [Auteur]
Bocquet, Emmanuel [Auteur]
Nawrocki, Laurent [Auteur]
Boyer, Emile [Auteur]
Meuric, Vincent [Auteur]
Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Titre de la revue :
Pathogens (Basel, Switzerland)
Nom court de la revue :
Pathogens
Numéro :
11
Date de publication :
2022-01-18
ISSN :
2076-0817
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
The effect of probiotics in improving or maintaining oral health in orthodontic patients is understudied. The aim of this study is to evaluate the effect of probiotic administration in addition to tooth brushing on clinical ...
Lire la suite >The effect of probiotics in improving or maintaining oral health in orthodontic patients is understudied. The aim of this study is to evaluate the effect of probiotic administration in addition to tooth brushing on clinical gingival inflammation, plaque formation, subgingival microbiota composition, and salivary biomarkers of inflammation in adolescents with fixed orthodontic appliances. The present study is a 6-month, double-blind, two-arm, placebo-controlled, single-center trial, in which 116 adolescent volunteers aged 12-16 years will be recruited from the patients of the orthodontics clinic of the University Hospital of Lille, France. Subjects who meet the eligibility criteria will be allocated to one of the following groups: (i) control: two placebo lozenges per day for 90 days together with regular oral hygiene, (ii) test: two probiotic lozenges per day for 90 days together with regular oral hygiene. Clinical assessment and biological sample collection will be performed at baseline, 3 and 6 months. In addition, compliance outcomes and adverse events will be monitored.Lire moins >
Lire la suite >The effect of probiotics in improving or maintaining oral health in orthodontic patients is understudied. The aim of this study is to evaluate the effect of probiotic administration in addition to tooth brushing on clinical gingival inflammation, plaque formation, subgingival microbiota composition, and salivary biomarkers of inflammation in adolescents with fixed orthodontic appliances. The present study is a 6-month, double-blind, two-arm, placebo-controlled, single-center trial, in which 116 adolescent volunteers aged 12-16 years will be recruited from the patients of the orthodontics clinic of the University Hospital of Lille, France. Subjects who meet the eligibility criteria will be allocated to one of the following groups: (i) control: two placebo lozenges per day for 90 days together with regular oral hygiene, (ii) test: two probiotic lozenges per day for 90 days together with regular oral hygiene. Clinical assessment and biological sample collection will be performed at baseline, 3 and 6 months. In addition, compliance outcomes and adverse events will be monitored.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Inserm
Université de Lille
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
U1008
Date de dépôt :
2022-04-13T07:12:01Z