Title :

Osmo-inelastic response of the intervertebral disc annulus fibrosus tissue

Author(s) :

Derrouiche, Amil [Auteur]
Zaouali, Ameni [Auteur]
Zairi, Fahmi [Auteur]
Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
Ismail, Jewan [Auteur]
Qu, Zhengwei [Auteur]
Chaabane, Makram [Auteur]
Zairi, Fahed [Auteur]

Journal title :

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

Abbreviated title :

Proc Inst Mech Eng H

Pages :

954411920936047

Publication date :

2020-07-03

ISSN :

2041-3033

Keyword(s) :

Annulus fibrosus
chemo-mechanical coupling
stress-stretch response
transversal strains
osmolarity
regional variation
strain-rate

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The aim of this article is to provide some insights on the osmo-inelastic response under stretching of annulus fibrosus of the intervertebral disc. Circumferentially oriented specimens of square cross section, extracted ...
Show more >The aim of this article is to provide some insights on the osmo-inelastic response under stretching of annulus fibrosus of the intervertebral disc. Circumferentially oriented specimens of square cross section, extracted from different regions of bovine cervical discs (ventral-lateral and dorsal-lateral), are tested under different strain-rates and saline concentrations within normal range of strains. An accurate optical strain measuring technique, based upon digital image correlation, is used in order to determine the full-field displacements in the lamellae and fibers planes of the layered soft tissue. Annulus stress-stretch relationships are measured along with full-field transversal strains in the two planes. The mechanical response is found hysteretic, rate-dependent and osmolarity-dependent with a Poisson's ratio higher than 0.5 in the fibers plane and negative (auxeticity) in the lamellae plane. While the stiffness presents a regional-dependency due to variations in collagen fibers content/orientation, the strain-rate sensitivity of the response is found independent on the region. A significant osmotic effect is found on both the auxetic response in the lamellae plane and the stiffness rate-sensitivity. These local experimental observations will result in more accurate chemo-mechanical modeling of the disc annulus and a clearer multi-scale understanding of the disc intervertebral function.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

IMT Lille Douai
INSERM
Institut Catholique Lille
Univ. Artois
Université de Lille

Collections :

• Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
• Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Submission date :

2022-06-15T13:59:36Z