Osmo-inelastic response of the intervertebral ...
Document type :
Article dans une revue scientifique: Article original
DOI :
PMID :
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Title :
Osmo-inelastic response of the intervertebral disc annulus fibrosus tissue.
Author(s) :
Derrouiche, A. [Auteur]
Zaouali, A. [Auteur]
Zairi, Fahmi [Auteur]
Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
Ismail, J. [Auteur]
Qu, Z. [Auteur]
Chaabane, M. [Auteur]
Zairi, Fahed [Auteur]
Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Zaouali, A. [Auteur]
Zairi, Fahmi [Auteur]

Laboratoire Génie Civil et géo-Environnement (LGCgE) - ULR 4515
Ismail, J. [Auteur]
Qu, Z. [Auteur]
Chaabane, M. [Auteur]
Zairi, Fahed [Auteur]

Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Journal title :
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Abbreviated title :
Proc Inst Mech Eng H
Pages :
954411920936047
Publication date :
2020-07-04
ISSN :
2041-3033
English keyword(s) :
osmolarity
strain-rate
regional variation
transversal strains
stress-stretch response
chemo-mechanical coupling
Annulus fibrosus
strain-rate
regional variation
transversal strains
stress-stretch response
chemo-mechanical coupling
Annulus fibrosus
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The aim of this article is to provide some insights on the osmo-inelastic response under stretching of annulus fibrosus of the intervertebral disc. Circumferentially oriented specimens of square cross section, extracted ...
Show more >The aim of this article is to provide some insights on the osmo-inelastic response under stretching of annulus fibrosus of the intervertebral disc. Circumferentially oriented specimens of square cross section, extracted from different regions of bovine cervical discs (ventral-lateral and dorsal-lateral), are tested under different strain-rates and saline concentrations within normal range of strains. An accurate optical strain measuring technique, based upon digital image correlation, is used in order to determine the full-field displacements in the lamellae and fibers planes of the layered soft tissue. Annulus stress–stretch relationships are measured along with full-field transversal strains in the two planes. The mechanical response is found hysteretic, rate-dependent and osmolarity-dependent with a Poisson’s ratio higher than 0.5 in the fibers plane and negative (auxeticity) in the lamellae plane. While the stiffness presents a regional-dependency due to variations in collagen fibers content/orientation, the strain-rate sensitivity of the response is found independent on the region. A significant osmotic effect is found on both the auxetic response in the lamellae plane and the stiffness rate-sensitivity. These local experimental observations will result in more accurate chemo-mechanical modeling of the disc annulus and a clearer multi-scale understanding of the disc intervertebral function.Show less >
Show more >The aim of this article is to provide some insights on the osmo-inelastic response under stretching of annulus fibrosus of the intervertebral disc. Circumferentially oriented specimens of square cross section, extracted from different regions of bovine cervical discs (ventral-lateral and dorsal-lateral), are tested under different strain-rates and saline concentrations within normal range of strains. An accurate optical strain measuring technique, based upon digital image correlation, is used in order to determine the full-field displacements in the lamellae and fibers planes of the layered soft tissue. Annulus stress–stretch relationships are measured along with full-field transversal strains in the two planes. The mechanical response is found hysteretic, rate-dependent and osmolarity-dependent with a Poisson’s ratio higher than 0.5 in the fibers plane and negative (auxeticity) in the lamellae plane. While the stiffness presents a regional-dependency due to variations in collagen fibers content/orientation, the strain-rate sensitivity of the response is found independent on the region. A significant osmotic effect is found on both the auxetic response in the lamellae plane and the stiffness rate-sensitivity. These local experimental observations will result in more accurate chemo-mechanical modeling of the disc annulus and a clearer multi-scale understanding of the disc intervertebral function.Show less >
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Submission date :
2023-12-13T05:21:41Z
2024-01-22T15:45:10Z
2024-01-22T15:45:10Z