Preventing the increase in the risk of ...
Document type :
Compte-rendu et recension critique d'ouvrage
Title :
Preventing the increase in the risk of bone failure in osteoporotic cervical spine vertebra with a novel computational approach
Author(s) :
Chenaifi, Khalil [Auteur]
Benabid, Yacine [Auteur]
Messellek, Ali Cherif [Auteur]
Ouali, Mohand Ould [Auteur]
Amrouche, abdelwaheb [Auteur]
Université d'Artois [UA]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Benabid, Yacine [Auteur]
Messellek, Ali Cherif [Auteur]
Ouali, Mohand Ould [Auteur]
Amrouche, abdelwaheb [Auteur]

Université d'Artois [UA]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Journal title :
Journal of Mechanics in Medicine and Biology
Publisher :
World Scientific Publishing
Publication date :
2023-04
ISSN :
0219-5194
HAL domain(s) :
Sciences de l'ingénieur [physics]
English abstract : [en]
Osteoporosis is a bone disease characterized by a low bone mass that may seriously lead to vertebral fractures. Nowadays, especially elderly people, are most vulnerable to this complication. Hence, it is essential to prevent ...
Show more >Osteoporosis is a bone disease characterized by a low bone mass that may seriously lead to vertebral fractures. Nowadays, especially elderly people, are most vulnerable to this complication. Hence, it is essential to prevent and predict the high-risk of mechanical stress that causes bone fractures. In this paper, a new computational methodology is developed to prevent the increase in the risk of bone failure in osteoporotic cervical vertebra based on mechanical stress assessment. The cortical bone thickness and the trabecular bone density from computed tomography (CT) scan data are the main initial input parameters for the computation. The methodology is based on a combination of finite element (FE) modeling of the lower cervical spine and the design of experiment (DoE) technique to establish surface responses assessing mechanical stress in healthy and osteoporotic vertebrae. The results reveal that the mechanical stress applied to an osteoporotic cervical vertebra is higher by an average of 35% compared to a healthy vertebra, respecting the applied conditions. Based thereon, a safety factor ([Formula: see text]) is introduced to predict and indicate the state of osteoporosis in the vertebra. A safety factor [Formula: see text] is found to correspond to a healthy state, 1.85 [Formula: see text] 2.45 for an osteopenic state, 1 [Formula: see text] 1.85 for an osteoporotic state, and [Formula: see text] 1 to indicate a severe osteoporosis state. The developed computational methodology consists of an efficient tool for clinicians to prevent early the risk of osteoporosis and also for engineers to design safer prostheses minimizing both mechanical stress concentration and stress shielding.Show less >
Show more >Osteoporosis is a bone disease characterized by a low bone mass that may seriously lead to vertebral fractures. Nowadays, especially elderly people, are most vulnerable to this complication. Hence, it is essential to prevent and predict the high-risk of mechanical stress that causes bone fractures. In this paper, a new computational methodology is developed to prevent the increase in the risk of bone failure in osteoporotic cervical vertebra based on mechanical stress assessment. The cortical bone thickness and the trabecular bone density from computed tomography (CT) scan data are the main initial input parameters for the computation. The methodology is based on a combination of finite element (FE) modeling of the lower cervical spine and the design of experiment (DoE) technique to establish surface responses assessing mechanical stress in healthy and osteoporotic vertebrae. The results reveal that the mechanical stress applied to an osteoporotic cervical vertebra is higher by an average of 35% compared to a healthy vertebra, respecting the applied conditions. Based thereon, a safety factor ([Formula: see text]) is introduced to predict and indicate the state of osteoporosis in the vertebra. A safety factor [Formula: see text] is found to correspond to a healthy state, 1.85 [Formula: see text] 2.45 for an osteopenic state, 1 [Formula: see text] 1.85 for an osteoporotic state, and [Formula: see text] 1 to indicate a severe osteoporosis state. The developed computational methodology consists of an efficient tool for clinicians to prevent early the risk of osteoporosis and also for engineers to design safer prostheses minimizing both mechanical stress concentration and stress shielding.Show less >
Language :
Anglais
Popular science :
Non
Source :