Title :

Sesamol–based terpenoids as promising bio‐sourced crop protection compounds against the wheat pathogen Zymoseptoria tritici

Author(s) :

Damiens, Audrey [Auteur]
Hautes Etudes d’Ingénieur [Lille] [HEI]
Transformation Intégrée de la Matière Renouvelable [TIMR]
Alebrahim, Mohammad Taghi [Auteur]
University of Mohaghegh Ardabili
Léonard, Estelle [Auteur]
Transformation Intégrée de la Matière Renouvelable [TIMR]
Fayeulle, Antoine [Auteur]
Transformation Intégrée de la Matière Renouvelable [TIMR]
Furman, Christophe [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Institut de Chimie Pharmaceutique Albert Lespagnol [ICPAL]
Hilbert, Jean-Louis [Auteur]
BioEcoAgro - Equipe 5 - Specialized Metabolites of Plant Origin
Siah, Ali [Auteur correspondant]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Billamboz, Muriel [Auteur correspondant]
Hautes Etudes d’Ingénieur [Lille] [HEI]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]

Journal title :

Pest Management Science

Pages :

2403-2414

Publisher :

Wiley

Publication date :

2021-01-08

ISSN :

1526-498X

English keyword(s) :

natural compounds
terpenoid
antifungal agents
biological screening
crop protection
sesamol

HAL domain(s) :

Sciences du Vivant [q-bio]/Biotechnologies
Sciences de l'environnement/Biodiversité et Ecologie
Sciences du Vivant [q-bio]/Biologie végétale/Phytopathologie et phytopharmacie
Sciences du Vivant [q-bio]/Ecologie, Environnement/Interactions entre organismes
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Mycologie

English abstract : [en]

BACKGROUNDResearch into environmentally friendly alternatives to conventional plant protection products, to promote sustainable agriculture and healthy food, is strongly encouraged.RESULTSIn this context, 20 naturally ...
Show more >BACKGROUNDResearch into environmentally friendly alternatives to conventional plant protection products, to promote sustainable agriculture and healthy food, is strongly encouraged.RESULTSIn this context, 20 naturally occurring terpenoids and phenolic compounds were selected and evaluated in vitro as crop protection compounds against Zymoseptoria tritici, the causal agent of Septoria tritici blotch of wheat. After selection of the most active compounds, some hemisynthetic modifications were conducted to modify their lipophilicity. These modifications led to the discovery of sesamol esters as promising antifungal agents, with IC50 around 10 μg/mL and a total absence of cytotoxicity against human cells.CONCLUSIONThese sesamol-based derivatives should be selected for further evaluations in planta to validate their use as wheat crop protection agents. Moreover, the importance of a balanced hydrophily/lipophilicity ratio should be further studied.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167

Source :

Harvested from HAL