Severe alcoholic hepatitis as precipitant ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Severe alcoholic hepatitis as precipitant for organ failure and ACLF.
Titre traduit :
Schwere Alkoholhepatitis als präzipitierender Faktor für Organversagen und ACLF
Auteur(s) :
Trebicka, Jonel [Auteur]
Universitätsklinikum Frankfurt
Louvet, Alexandre [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Arroyo, Vincente [Auteur]
European Foundation for Study of Chronic Liver Failure [Barcelona] [EF CLIF]
Jalan, Rajiv [Auteur]
University College of London [London] [UCL]
Shah, Vijay H. [Auteur]
Mayo Clinic [Rochester]
Moreau, Richard [Auteur]
Centre de recherche biomédicale Bichat-Beaujon [CRB3]
Centre de recherche sur l'Inflammation [CRI (UMR_S_1149 / ERL_8252 / U1149)]
Universitätsklinikum Frankfurt
Louvet, Alexandre [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Arroyo, Vincente [Auteur]
European Foundation for Study of Chronic Liver Failure [Barcelona] [EF CLIF]
Jalan, Rajiv [Auteur]
University College of London [London] [UCL]
Shah, Vijay H. [Auteur]
Mayo Clinic [Rochester]
Moreau, Richard [Auteur]
Centre de recherche biomédicale Bichat-Beaujon [CRB3]
Centre de recherche sur l'Inflammation [CRI (UMR_S_1149 / ERL_8252 / U1149)]
Titre de la revue :
Zeitschrift für Gastroenterologie
Nom court de la revue :
Z Gastroenterol
Numéro :
60
Pagination :
67-76
Date de publication :
2022-01-20
ISSN :
1439-7803
Mot(s)-clé(s) en anglais :
ASH
ACLF
systemic inflammation
liver transplantation
ACLF
systemic inflammation
liver transplantation
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Alcoholic hepatitis is the acute deterioration of alcoholic liver disease with rapid onset or worsening of jaundice, which in severe cases, may transition to acute-on-chronic liver failure with extremely high short-term ...
Lire la suite >Alcoholic hepatitis is the acute deterioration of alcoholic liver disease with rapid onset or worsening of jaundice, which in severe cases, may transition to acute-on-chronic liver failure with extremely high short-term mortality, increasing with the number and severity of hepatic and extra-hepatic organ dysfunction. Diagnosis and treatment are insufficient and challenging, especially due to the complex, multi-factorial and as yet not fully understood pathogenesis. While current management is limited to steroids and best supportive care, debate is ongoing concerning liver transplantation for selected patients, and several novel approaches are under way with mixed results. These drawbacks in disease management together with increasing prevalence in Germany, and generally in Western countries, constitute an unmet need for the healthcare systems. This review tries to summarize the current status of these aspects and provides an overview for pathogenesis, management and potential future treatments.Lire moins >
Lire la suite >Alcoholic hepatitis is the acute deterioration of alcoholic liver disease with rapid onset or worsening of jaundice, which in severe cases, may transition to acute-on-chronic liver failure with extremely high short-term mortality, increasing with the number and severity of hepatic and extra-hepatic organ dysfunction. Diagnosis and treatment are insufficient and challenging, especially due to the complex, multi-factorial and as yet not fully understood pathogenesis. While current management is limited to steroids and best supportive care, debate is ongoing concerning liver transplantation for selected patients, and several novel approaches are under way with mixed results. These drawbacks in disease management together with increasing prevalence in Germany, and generally in Western countries, constitute an unmet need for the healthcare systems. This review tries to summarize the current status of these aspects and provides an overview for pathogenesis, management and potential future treatments.Lire moins >
Langue :
Allemand
Anglais
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Date de dépôt :
2024-01-12T02:28:23Z
2024-01-26T13:04:03Z
2024-01-26T13:04:03Z