Title :

MegaNatural (R)-BP grape seed extract and maintenance of normal blood pressure: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

Author(s) :

Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Bohn, T. [Auteur]
European Food Safety Authority [EFSA]
Castenmiller, J. [Auteur]
De Henauw, S. [Auteur]
Hirsch-Ernst, K. I. [Auteur]
Knutsen, H. K. [Auteur]
Maciuk, A. [Auteur]
Mangelsdorf, I. [Auteur]
Mcardle, H. J. [Auteur]
Naska, A. [Auteur]
Pelaez, C. [Auteur]
Pentieva, K. [Auteur]
Siani, A. [Auteur]
Thies, F. [Auteur]
Tsabouri, S. [Auteur]
Vinceti, M. [Auteur]

Journal title :

EFSA Journal

Abbreviated title :

EFSA J.

Volume number :

19

Pages :

-

Publication date :

2021-09-22

ISSN :

1831-4732

English keyword(s) :

MegaNatural (R)-BP
grape seed extract
blood pressure
health claim

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Following an application from Praline i Cokolada j.d.o.o. submitted for authorisation of a health claimpursuant to Article 13(5) of Regulation (EC) No 1924/2006viathe Competent Authority of Croatia, theEFSA Panel on ...
Show more >Following an application from Praline i Cokolada j.d.o.o. submitted for authorisation of a health claimpursuant to Article 13(5) of Regulation (EC) No 1924/2006viathe Competent Authority of Croatia, theEFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion onthe scientific substantiation of a health claim related to MegaNatural®-BP grape seed extract andmaintenance of normal blood pressure. The scope of the application was proposed to fall under ahealth claim based on newly developed scientific evidence. MegaNatural®-BP, a grape seed extractstandardised for total phenolics, gallic acid and the catechin and epicatechin content, is sufficientlycharacterised. The proposed claimed effect, maintenance of normal blood pressure (BP), is a beneficialphysiological effect. Among the two human intervention studies provided from which conclusions couldbe drawn, one showed an effect of MegaNatural®-BP (300 mg/day) on BP in adults with normal andhigh normal BP when consumed daily for 6 weeks, whereas the second study did not show an effectof MegaNatural®-BP at the same daily dose consumed for 8 weeks in adults with normal and highnormal blood pressure or stage 1 hypertension. The evidence provided did not establish a plausiblemechanism by which the food could exert the claimed effectin vivoin humans. The evidence providedis insufficient to establish a cause and effect relationship between the consumption of MegaNatural®-BP and maintenance of normal blood pressure.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-12T06:12:16Z
2024-03-01T10:57:37Z