Intracerebral haemorrhage
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
Permalink :
Title :
Intracerebral haemorrhage
Author(s) :
Puy, Laurent [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Parry-Jones, Adrian R. [Auteur]
University of Manchester [Manchester]
Sandset, Else Charlotte [Auteur]
Oslo University Hospital [Oslo]
Dowlatshahi, Dar [Auteur]
University of Ottawa [Ottawa]
Ottawa Hospital Research Institute [Ottawa] [OHRI]
Ziai, Wendy [Auteur]
Johns Hopkins University School of Medicine [Baltimore]
Cordonnier, Charlotte [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Parry-Jones, Adrian R. [Auteur]
University of Manchester [Manchester]
Sandset, Else Charlotte [Auteur]
Oslo University Hospital [Oslo]
Dowlatshahi, Dar [Auteur]
University of Ottawa [Ottawa]
Ottawa Hospital Research Institute [Ottawa] [OHRI]
Ziai, Wendy [Auteur]
Johns Hopkins University School of Medicine [Baltimore]
Cordonnier, Charlotte [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Journal title :
Nature reviews Disease primers
Abbreviated title :
Nat Rev Dis Primers
Volume number :
9
Pages :
14
Publisher :
Nature Publishing Group
Publication date :
2023-03-16
ISSN :
2056-676X
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke-related mortality and dependency: ...
Show more >Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke-related mortality and dependency: only half of patients survive for 1 year after ICH, and patients who survive have sequelae that affect their quality of life. The incidence of ICH has increased in the past few decades with shifts in the underlying vessel disease over time as vascular prevention has improved and use of antithrombotic agents has increased. The pathophysiology of ICH is complex and encompasses mechanical mass effect, haematoma expansion and secondary injury. Identifying the causes of ICH and predicting the vital and functional outcome of patients and their long-term vascular risk have improved in the past decade; however, no specific treatment is available for ICH. ICH remains a medical emergency, with prevention of haematoma expansion as the key therapeutic target. After discharge, secondary prevention and management of vascular risk factors in patients remains challenging and is based on an individual benefit–risk balance evaluation.Show less >
Show more >Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke-related mortality and dependency: only half of patients survive for 1 year after ICH, and patients who survive have sequelae that affect their quality of life. The incidence of ICH has increased in the past few decades with shifts in the underlying vessel disease over time as vascular prevention has improved and use of antithrombotic agents has increased. The pathophysiology of ICH is complex and encompasses mechanical mass effect, haematoma expansion and secondary injury. Identifying the causes of ICH and predicting the vital and functional outcome of patients and their long-term vascular risk have improved in the past decade; however, no specific treatment is available for ICH. ICH remains a medical emergency, with prevention of haematoma expansion as the key therapeutic target. After discharge, secondary prevention and management of vascular risk factors in patients remains challenging and is based on an individual benefit–risk balance evaluation.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Research team(s) :
Troubles cognitifs dégénératifs et vasculaires
Submission date :
2024-01-15T23:24:36Z
2024-12-04T14:10:04Z
2024-12-04T14:10:04Z