Titre :

Neurofilaments contribution in clinic: state of the art.

Auteur(s) :

Delaby, C. [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Bousiges, O. [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Bouvier, D. [Auteur]
CHU Gabriel Montpied [Clermont-Ferrand]
Fillée, C. [Auteur]
Université Catholique de Louvain = Catholic University of Louvain [UCL]
Fourier, A. [Auteur]
Groupement Hospitalier Lyon-Est [GHE]
Mondésert, E. [Auteur]
Hôpital Gui de Chauliac [CHU Montpellier]
Nezry, N. [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Omar, S. [Auteur]
Quadrio, I. [Auteur]
Laboratoire de Biologie Médicale MultiSites [Bron] [LBMMS]
Rucheton, B. [Auteur]
Institut Bergonié [Bordeaux]
Schraen, Susanna [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Van Pesch, V. [Auteur]
Cliniques Universitaires Saint-Luc [Bruxelles]
Vicca, S. [Auteur]
Hôpital Necker - Enfants Malades [AP-HP]
Lehmann, S. [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Bedel, A. [Auteur]
CHU de Bordeaux Pellegrin [Bordeaux]

Titre de la revue :

Frontiers in Aging Neuroscience

Nom court de la revue :

Front Aging Neurosci

Numéro :

14

Pagination :

1034684

Éditeur :

Frontiers

Date de publication :

2022-11-22

ISSN :

1663-4365

Mot(s)-clé(s) :

neurofilament
biomarkers
neurological and neurodegenerative diseases
cut-off
biological fluids

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. This field of neurology has evolved considerably in recent years with the improvement ...
Lire la suite >Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. This field of neurology has evolved considerably in recent years with the improvement of analytical methods, allowing the detection of biomarkers not only in cerebrospinal fluid (CSF) but also in less invasive fluids like blood. These advances greatly facilitate the repeated quantification of biomarkers, including at asymptomatic stages of the disease. Among the various informative biomarkers of neurological disorders, neurofilaments (NfL) have proven to be of particular interest in many contexts, such as neurodegenerative diseases, traumatic brain injury, multiple sclerosis, stroke, and cancer. Here we discuss these different pathologies and the potential value of NfL assay in the management of these patients, both for diagnosis and prognosis. We also describe the added value of NfL compared to other biomarkers currently used to monitor the diseases described in this review.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Date de dépôt :

2024-01-16T00:20:34Z
2024-10-16T09:45:59Z