Corpus callosum damage to account for ...
Type de document :
Article dans une revue scientifique
URL permanente :
Titre :
Corpus callosum damage to account for cognitive, affective, and social-cognitive dysfunctions in multiple sclerosis: A model of callosal disconnection syndrome?
Auteur(s) :
Degraeve, Béatrice [Auteur]
Sequeira, Henrique [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Mecheri, Halima [Auteur]
Lenne, Bruno [Auteur]
Sequeira, Henrique [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Mecheri, Halima [Auteur]
Lenne, Bruno [Auteur]
Titre de la revue :
Multiple Sclerosis Journal
Nom court de la revue :
Mult Scler
Numéro :
29
Pagination :
160-168
Éditeur :
SAGE Publications
Date de publication :
2022-04-27
Discipline(s) HAL :
Sciences cognitives
Résumé en anglais : [en]
The corpus callosum (CC) is the major commissure interconnecting the two hemispheres and is particularly affected in multiple sclerosis (MS). In the present review, we aimed to investigate the role played by callosal damages ...
Lire la suite >The corpus callosum (CC) is the major commissure interconnecting the two hemispheres and is particularly affected in multiple sclerosis (MS). In the present review, we aimed to investigate the role played by callosal damages in the pathogenesis of MS-related dysfunctions and examine whether a model of callosal disconnection syndrome is a valid model for MS. For this purpose, we will first review structural and functional evidence of callosal pathology in MS. Second, we will account for the potential role of CC abnormalities in MS-related dysfunctions. Finally, we will report data concurring with a “multiple disconnection hypothesis” that has been proposed to explain those dysfunctions, and we will examine evidence pointing toward MS as a “callosal disconnection syndrome.” We will end by discussing the contribution of this interpretation to the understanding of MS and MS-related deficits.Lire moins >
Lire la suite >The corpus callosum (CC) is the major commissure interconnecting the two hemispheres and is particularly affected in multiple sclerosis (MS). In the present review, we aimed to investigate the role played by callosal damages in the pathogenesis of MS-related dysfunctions and examine whether a model of callosal disconnection syndrome is a valid model for MS. For this purpose, we will first review structural and functional evidence of callosal pathology in MS. Second, we will account for the potential role of CC abnormalities in MS-related dysfunctions. Finally, we will report data concurring with a “multiple disconnection hypothesis” that has been proposed to explain those dysfunctions, and we will examine evidence pointing toward MS as a “callosal disconnection syndrome.” We will end by discussing the contribution of this interpretation to the understanding of MS and MS-related deficits.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CNRS
CHU Lille
CNRS
CHU Lille
Équipe(s) de recherche :
Équipe Dynamique Émotionnelle et Pathologies (DEEP)
Date de dépôt :
2024-01-17T14:27:14Z