Title :

NIFT-P: Are they indolent tumors? Results of a multi-institutional study.

Author(s) :

Chereau, Nathalie [Auteur]
Sorbonne Université [SU]
Greilsamer, Tristan [Auteur]
Institut des Maladies de l'Appareil Digestif
Mirallié, Eric [Auteur]
Institut des Maladies de l'Appareil Digestif
Sadowski, Samira M. [Auteur]
Pusztaszeri, Marc [Auteur]
Triponez, Frederic [Auteur]
Baud, Gregory [Auteur]
Recherche translationnelle sur le diabète - U 1190 [RTD]
Pattou, Francois [Auteur]
Recherche translationnelle sur le diabète (RTD) - U1190
Christou, Niki [Auteur]
CHU Limoges
Mathonnet, Muriel [Auteur]
CHU Limoges
Brunaud, Laurent [Auteur]
Université de Lorraine [UL]
Santucci, Nicolas [Auteur]
CHU Dijon
Goudet, Pierre [Auteur]
CHU Dijon
Guérin, Carole [Auteur]
Aix Marseille Université [AMU]
Sebag, Frédéric [Auteur]
Aix Marseille Université [AMU]
Donatini, Gianluca [Auteur]
Université de Poitiers = University of Poitiers [UP]
Kraimps, Jean-Louis [Auteur]
Université de Poitiers = University of Poitiers [UP]
Tissier, Frédérique [Auteur]
Sorbonne Université [SU]
Lussey, Charlotte [Auteur]
Sorbonne Université [SU]
Leenhardt, Laurence [Auteur]
Sorbonne Université [SU]
Menegaux, Fabrice [Auteur]
Sorbonne Université [SU]

Journal title :

Surgery

Abbreviated title :

Surgery

Volume number :

165

Pages :

12-16

Publication date :

2018-11-09

ISSN :

1532-7361

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Encapsulated follicular variant of papillary thyroid carcinoma has recently been reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features on the basis of its highly indolent ...
Show more >Background Encapsulated follicular variant of papillary thyroid carcinoma has recently been reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features on the basis of its highly indolent behavior, as proposed by an international group of experienced thyroid pathologists. Methods All patients from 9 high-volume endocrine surgery departments who underwent surgery between 2005 and 2015 and whose final surgical pathology revealed noninvasive follicular thyroid neoplasm with papillary-like nuclear features (>10 mm) were included in this study. The primary outcome was to determine the potential for recurrent disease in these patients. Results Among the 363 patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear features, 76% were female with a median age of 50 years (5–86 years); 345 patients (95%) underwent total thyroidectomy. A total of 65 patients had an associated micropapillary thyroid carcinoma. In the group of 133 patients who underwent prophylactic lymph node dissection (37%), 1 patient had a micrometastasis but with an associated micropapillary thyroid carcinoma. Over a median follow-up period of 5 years, 1 patient with an associated micropapillary thyroid carcinoma had recurrent disease at 6 years. All patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear features without micropapillary thyroid carcinoma had no lymph node metastasis or recurrent disease. Conclusion We found that noninvasive follicular thyroid neoplasm with papillary-like nuclear features presents with indolent behavior. However, the identification of an associated micropapillary thyroid carcinoma should be carefully evaluated because it could be a factor for lymph node metastasis and/or of recurrence.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Recherche translationnelle sur le diabète (RTD) - U1190

Submission date :

2024-01-19T23:56:11Z
2024-10-16T08:25:09Z