Titre :

The ebmt activity survey report 2017: a focus on allogeneic hct for nonmalignant indications and on the use of non-hct cell therapies

Auteur(s) :

Passweg, Jakob [Auteur]
Baldomero, Helen [Auteur]
Basak, Grzegorz Wladyslaw [Auteur]
Chabannon, Christian [Auteur]
Corbacioglu, Selim [Auteur]
Duarte, Rafael F. [Auteur]
Kuball, Jurgen [Auteur]
Lankester, Arjan [Auteur]
Montoto, Silvia [Auteur]
Peffault de Latour, Regis [Auteur]
Snowden, John A. [Auteur]
Styczynski, Jan [Auteur]
Yakoub-Agha, Ibrahim [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Arat, Mutlu [Auteur]
Mohty, Mohamad [Auteur]
Kroger, Nicolaus [Auteur]

Titre de la revue :

Bone Marrow Transplantation

Nom court de la revue :

Bone Marrow Transplant.

Numéro :

54

Pagination :

1575–1585

Date de publication :

2019-10

ISSN :

1476-5365

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Hematopoietic cell transplantation (HCT) is widely used for acquired and congenital disorders of the hematopoietic system. Number of transplants done in Europe and associated countries continues to rise with 45,418 HCT in ...
Lire la suite >Hematopoietic cell transplantation (HCT) is widely used for acquired and congenital disorders of the hematopoietic system. Number of transplants done in Europe and associated countries continues to rise with 45,418 HCT in 41,100 patients [(17,155 allogeneic (42%) and 23,945 autologous (58%)] reported by 683 centers in 50 countries in 2017. Main indications were myeloid malignancies 10,147 (25%; 96% allogeneic), lymphoid malignancies 26,488 (64%; 19% allogeneic), solid tumors 1,607 (3.9%; 2% allogeneic), and nonmalignant disorders 2,667 (7%; 81% allogeneic). Trends in donor choice seen before continue, with growing numbers of haploidentical HCT and decreasing use of cord blood. Of interest is that after many years of continued growth, the number of patients receiving an allogeneic HCT for marrow failure is decreasing slightly (p < 0.001). Such a change may be explained by the use of thrombopoietin analogs in aplastic anemia patients. Other nonmalignant indications, however continue to grow, most importantly HCT for hemoglobinopathies by 36%, equally for thalassemias and sickle cell disease. Non-HCT cell therapies have increased by 28% since 2015 and genetically modified T cells is type of cell therapy with the fastest growth. These annual reports reflect current activity and trends and are useful for health-care planning.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2024-01-30T10:26:56Z
2024-01-31T11:31:24Z