Titre :

Radiological assessment of mandibular invasion in squamous cell carcinoma of the oral cavity and oropharynx

Auteur(s) :

Bouhir, S. [Auteur]
Université de Lille
Mortuaire, Geoffrey [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Dubrulle-Berthelot, F. [Auteur]
Université de Lille
Leroy, Xavier [Auteur]
Université de Lille
Deken-Delannoy, V. [Auteur]
Université de Lille
Rysman, Benedicte [Auteur]
Université de Lille
Chevalier, Dominique [Auteur]
Université de Lille
Mouawad, Francois [Auteur]
Université de Lille

Titre de la revue :

European Annals of Otorhinolaryngology, Head and Neck Diseases

Nom court de la revue :

Eur Ann Otorhinolaryngol Head Neck Dis

Numéro :

136

Pagination :

361-366

Date de publication :

2019-10

ISSN :

1879-730X

Mot(s)-clé(s) en anglais :

Magnetic resonance imaging
Sensitivity and specificity
Computed tomography
Oropharyngeal and oral cavity cancer
Mandibular bone invasion

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

BACKGROUND: Preoperative assessment of mandibular bone invasion in squamous cell carcinoma of the oral cavity and oropharynx is crucial for optimizing bone resection. The principal aim of this study was to evaluate the ...
Lire la suite >BACKGROUND: Preoperative assessment of mandibular bone invasion in squamous cell carcinoma of the oral cavity and oropharynx is crucial for optimizing bone resection. The principal aim of this study was to evaluate the diagnostic value of CT and MR imaging for the diagnosis of mandibular bone invasion compared to the histological reference. In addition, we assessed the survival impact of bone invasion. METHODS: A single-center retrospective study included all consecutive patients treated by mandibular bone interruption for squamous cell carcinoma of the oral cavity and/or oropharynx. RESULTS: Sixty-eight patients were included. Prevalence of bone invasion on histology was 43%. Sensitivity, specificity and positive and negative predictive value were respectively 70%, 71%, 66% and 76% for CT compared with histologic analysis, 83%, 50%, 59% and 78% for MRI, and 83%, 62% 62%, 83% for associated CT and MRI. The two tests showed good agreement, with kappa index 0.69 (95% CI, 0.49-0.89) (P<0.0001). There was no difference in overall survival (log-rank>0.70) between the groups with and without bone invasion. CONCLUSIONS: CT and MRI are complementary for preoperative assessment of mandibular bone invasion, be it cortical and/or medullary, and in some cases may allow mandibular bone-sparing.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2024-01-30T10:27:58Z
2024-02-15T12:28:57Z