Titre :

Treatment of Eosinophilic Annular Erythema: Retrospective multicenter study and literature review.

Auteur(s) :

Chastagner, M. [Auteur]
Université Claude Bernard Lyon 1 [UCBL]
Hôpital Edouard Herriot [CHU - HCL]
Shourik, J. [Auteur]
CHU Tenon [AP-HP]
Jachiet, M. [Auteur]
Hopital Saint-Louis [AP-HP] [AP-HP]
Service de Dermatologie [AP-HP Hôpital Saint-Louis]
Battistella, M. [Auteur]
Hopital Saint-Louis [AP-HP] [AP-HP]
Immunologie humaine, physiopathologie & immunothérapie [HIPI (UMR_S_976 / U976)]
Lefevre, Guillaume [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Gibier, Jean-Baptiste [Auteur]
Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers = Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 [CANTHER]
Aubert, H. [Auteur]
Service de dermatologie [Nantes]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Musquer, M. [Auteur]
Descamps, V. [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Deschamps, L. [Auteur]
Chosidow, O. [Auteur]
Hôpital Henri Mondor
Université Paris-Est Créteil Val-de-Marne - Paris 12 [UPEC UP12]
Dynamic Microbiology - EA 7380 [DYNAMIC]
Ortonne, N. [Auteur]
Groh, M. [Auteur]
Hôpital Foch [Suresnes]
Bernier, M. [Auteur]
Jullien, D. [Auteur]
Chasset, F. [Auteur]
Staumont, delphine [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Bouaziz, J. D. [Auteur]
Kanikatis, J. [Auteur]
Villani, A. P. [Auteur]

Titre de la revue :

Annales de Dermatologie et de Vénéréologie

Éditeur :

Elsevier Masson

Date de publication :

2021-11-06

ISSN :

0151-9638

Mot(s)-clé(s) en anglais :

Eosinophilic annular erythema
Eosinophil
Wells syndrome
Eosinophilic cellulitis
Treatment

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

BackgroundEosinophilic annular erythema (EAE) is a rare eosinophil-related skin disease which typically manifests with annular erythematous plaques and severe pruritus. Besides the diagnosis, the treatment of EAE is ...
Lire la suite >BackgroundEosinophilic annular erythema (EAE) is a rare eosinophil-related skin disease which typically manifests with annular erythematous plaques and severe pruritus. Besides the diagnosis, the treatment of EAE is challenging since relevant published data are sparse.MethodsThe aim of this study was to assess the underlying diseases, treatments and outcomes of patients with EAE. To this end, we conducted a retrospective multicenter study and a systematic review of the MEDLINE database.ResultsWe included 18 patients with EAE followed in 8 centers. The MEDLINE database search yielded 37 relevant publications reporting 55 cases of EAE with 106 treatment sequences. The most common and efficient treatments included topical or systemic corticosteroids, hydroxychloroquine and dapsone. In refractory patients, a combination of systemic corticosteroids with hydroxychloroquine was associated with 88% of complete clinical response.DiscussionTo improve the management of EAE patients, we discuss the following treatment strategy: in topical steroid-resistant patients, hydroxychloroquine can be given as first-line systemic treatment. Dapsone, hydroxychloroquine or systemic corticosteroids are second-line options to consider. Last, monoclonal antibodies or JAK inhibitors targeting type 2 inflammation could represent promising last-resort options in refractory patients.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277

Source :

Harvested from HAL