Title :

Metabolic syndrome, malnutrition, and its associations with cardiovascular and all-cause mortality in hemodialysis patients: Follow-up for three years

Author(s) :

El Ati, Zohra [Auteur]
Machfar, Hanene [Auteur]
Boussafa, Hamza [Auteur]
Ati, Nidhal [Auteur]
Omrane Sioud, Olfaben [Auteur]
Zantour, Baha [Auteur]
Bouzidi, Hassen [Auteur]
Elati, Mohamed [Auteur correspondant]
Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers = Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 [CANTHER]
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]

Journal title :

Saudi Journal of Kidney Diseases and Transplantation

Pages :

129

Publisher :

Wolters Kluwer

Publication date :

2020

ISSN :

1319-2442

HAL domain(s) :

Sciences du Vivant [q-bio]
Informatique [cs]

English abstract : [en]

ABSTRACT.Metabolic disorder contributes to the increasein the mortality rate of patients onhemodialysis(HD). The aim of this study was toestimate the prevalence of metabolic syndrome(MS) and malnutritionin patients ...
Show more >ABSTRACT.Metabolic disorder contributes to the increasein the mortality rate of patients onhemodialysis(HD). The aim of this study was toestimate the prevalence of metabolic syndrome(MS) and malnutritionin patients onmaintenanceHD and to evaluate their influence oncardiovascular and all-cause mortalityduring the follow-up. We carried outa prospective cross-sectional studyin which we enrolled 100 patients from a single center whohad been followed upfor three years.Collected data includeddemographic characteristics, detailedmedical history,clinical variables, MSvariables, nutritional status, and laboratory findings. The outcomes werethe occurrence of a cardiovascular event and cardiovascular or all-cause mortality during thefollow-up period.The Statistical Package for the Social Sciences softwarewas usedfor statisticalanalysis. Whereas 50% of patients had MS, 23% showed evidence of malnutrition. Patients withMS were olderand had more preexisting cardiovasculardiseases(CVDs). All patients werefollowed for 36 months. During this time, 19patients with MS and 14 patients without MS died(38% vs. 28%; P = 0.19), most frequently of CVD.Mean survival time was 71.52 ± 42.1monthsfor MS groupversus 92.06 ± 65 monthsfor non-MS group, but the difference was notsignificant.MS was related with a higher cardiovascular mortality, while malnutrition was significantlyassociated with all-cause mortality.Our data showedthatMS was not related to cardiovascular orall-cause mortality in HD patients and didnot influence survival. The independent risk factors forall-causemortality were older age, preexisting CVD, and malnutrition.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277

Source :

Harvested from HAL