Titre :

Sex disparities in cardiogenic shock: Insights from the FRENSHOCK registry

Auteur(s) :

Manzo-Silberman, Stéphane [Auteur correspondant]
Institut de cardiologie [CHU Pitié-Salpêtrière]
Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis [IThEM - U1140]
Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé [CREATIS]
Assistance Publique - Hôpitaux de Marseille [APHM]
Mediterranean Association for Research and Studies in Cardiology [MARS cardio]
Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
Martin, Anne-Céline [Auteur]
Hôpital Européen Georges Pompidou [APHP] [HEGP]
Boissier, Florence [Auteur]
CIC Poitiers – Centre d'investigation clinique de Poitiers [CIC 1402]
Hauw-Berlemont, Caroline [Auteur]
Aissaoui, Nadia [Auteur]
Lamblin, Nicolas [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Roubille, François [Auteur]
Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] [PhyMedExp]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Bonnefoy, Eric [Auteur]
Bonello, Laurent [Auteur]
Elbaz, Meyer [Auteur]
Schurtz, Guillaume [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Morel, Olivier [Auteur]
Leurent, Guillaume [Auteur]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Levy, Bruno [Auteur]
Jouve, Bernard [Auteur]
Harbaoui, Brahim [Auteur]
Vanzetto, Gérald [Auteur]
Combaret, Nicolas [Auteur]
Lattucca, Benoit [Auteur]
Champion, Sébastien [Auteur]
Lim, Pascal [Auteur]
Institut Mondor de Recherche Biomédicale [IMRB]
Bruel, Cédric [Auteur]
Schneider, Francis [Auteur]
Seronde, Marie-France [Auteur]
Bataille, Vincent [Auteur]
Gerbaud, Edouard [Auteur]
Puymirat, Etienne [Auteur]
Delmas, Clément [Auteur correspondant]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]

Titre de la revue :

Journal of Critical Care

Pagination :

154785

Éditeur :

WB Saunders

Date de publication :

2024-08

ISSN :

0883-9441

Mot(s)-clé(s) en anglais :

Cardiogenic shock
Epidemiology
Management
Prognosis
Sex

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Background: Cardiogenic shock (CS) is the most severe form of acute heart failure. Discrepancies have been reported between sexes regarding delays, pathways and invasive strategies in CS complicating acute myocardial ...
Lire la suite >Background: Cardiogenic shock (CS) is the most severe form of acute heart failure. Discrepancies have been reported between sexes regarding delays, pathways and invasive strategies in CS complicating acute myocardial infarction. However, effect of sex on the prognosis of unselected CS remains controversial.Objectives: The aim was to analyze the impact of sex on aetiology, management and prognosis of CS.Methods: The FRENSHOCK registry included all CS admitted in 49 French Intensive Care Units (ICU) and Intensive Cardiac Care Units (ICCU) between April and October 2016.Results: Among the 772 CS patients included, 220 were women (28.5%). Women were older, less smokers, with less history of ischemic cardiac disease (20.5% vs 33.6%) than men. At admission, women presented less cardiac arrest (5.5 vs 12.2%), less mottling (32.5 vs 41.4%) and higher LVEF (30 ± 14 vs 25 ± 13%). Women were more often managed via emergency department while men were directly admitted at ICU/ICCU. Ischemia was the most frequent trigger irrespective of sex (36.4% in women vs 38.2%) but women had less coronary angiogram and PCI (45.9% vs 54% and 24.1 vs 31.3%, respectively). We found no major difference in medication and organ support. Thirty-day mortality (26.4 vs 26.5%), transplant or permanent assist device were similar in both sexes.Conclusion: Despite some more favorable parameters in initial presentation and no significant difference in medication and support, women shared similar poor prognosis than men. Further analysis is required to cover the lasting gap in knowledge regarding sex specificities to distinguish between differences and inequalities. NCT02703038.Lire moins >

Langue :

Anglais

Vulgarisation :

Non

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167

Source :

Harvested from HAL