Title :

Cancer and multiple sclerosis: 2023 recommendations from the French Multiple Sclerosis Society

Author(s) :

Collongues, Nicolas [Auteur]
Les Hôpitaux Universitaires de Strasbourg [HUS]
Durand-Dubief, F. [Auteur]
Lebrun-Frenay, C. [Auteur]
Audoin, B. [Auteur]
Ayrignac, X. [Auteur]
Bensa, C. [Auteur]
Bigaut, K. [Auteur]
Bourre, B. [Auteur]
Carra-Dalliã¨re, C. [Auteur]
Ciron, J. [Auteur]
Defer, G. [Auteur]
Kwiatkowski, Arnaud [Auteur]
Université catholique de Lille [UCL]
Leray, E. [Auteur]
Maillart, E. [Auteur]
Marignier, R. [Auteur]
Mathey, G. [Auteur]
Morel, N. [Auteur]
Thouvenot, E. [Auteur]
Zephir, Helene [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Boucher, Julie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Boutiã¨re, C. [Auteur]
Branger, P. [Auteur]
da Silva, A. [Auteur]
Demortiã¨re, S. [Auteur]
Guillaume, M. [Auteur]
Hebant, B. [Auteur]
Januel, E. [Auteur]
Kerbrat, A. [Auteur]
Manchon, E. [Auteur]
Moisset, X. [Auteur]
Montcuquet, A. [Auteur]
Pierret, C. [Auteur]
Pique, J. [Auteur]
Poupart, Julie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Prunis, C. [Auteur]
Roux, T. [Auteur]
Schmitt, P. [Auteur]
Androdias, G. [Auteur]
Cohen, M. [Auteur]

Journal title :

Multiple Sclerosis Journal

Abbreviated title :

Mult. Scler. J.

Volume number :

30

Pages :

-

Publisher :

SAGE Journals

Publication date :

2024-03-12

ISSN :

1352-4585

English keyword(s) :

Multiple sclerosis
cancer
disease-modifying treatments
checkpoint inhibitors
immunotherapy

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background: Epidemiological data reveal that 45% of persons with multiple sclerosis (PwMS) in France are more than 50 years. This population more than 50 is more susceptible to cancer, and this risk may be increased by ...
Show more >Background: Epidemiological data reveal that 45% of persons with multiple sclerosis (PwMS) in France are more than 50 years. This population more than 50 is more susceptible to cancer, and this risk may be increased by frequent use of immunosuppressive drugs. Consequently, concerns have arisen about the potential increased risk of cancer in PwMS and how patients should be screened and managed in terms of cancer risk. Objective: To develop evidence-based recommendations to manage the coexistence of cancer and multiple sclerosis (MS). Methods: The French Group for Recommendations in MS collected articles from PubMed and university databases covering the period January 1975 through June 2022. The RAND/UCLA method was employed to achieve formal consensus. MS experts comprehensively reviewed the full-text articles and developed the initial recommendations. A group of multidisciplinary health care specialists then validated the final proposal. Results: Five key questions were addressed, encompassing various topics such as cancer screening before or after initiating a disease-modifying therapy (DMT), appropriate management of MS in the context of cancer, recommended follow-up for cancer in patients receiving a DMT, and the potential reintroduction of a DMT after initial cancer treatment. A strong consensus was reached for all 31 recommendations. Conclusion: These recommendations propose a strategic approach to managing cancer risk in PwMS.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Submission date :

2024-05-15T21:45:18Z
2024-06-24T09:37:12Z
2025-01-22T10:37:01Z