Title :

Global differences in the management of alcohol-associated hepatitis.

Author(s) :

Blaney, H. [Auteur]
Díaz, L. A. [Auteur]
Li, N. [Auteur]
Malhi, G. [Auteur]
Mortuza, R. [Auteur]
Qi, X. [Auteur]
Kulkarni, A. V. [Auteur]
Bataller, R. [Auteur]
Cabezas, J. [Auteur]
Louvet, Alexandre [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Tapper, E. B. [Auteur]
Arab, Juan Pablo [Auteur]
Pontificia Universidad Católica de Chile [UC]

Journal title :

The Lancet Gastroenterology & Hepatology

Abbreviated title :

Lancet Gastroenterol Hepatol

Volume number :

9

Pages :

972-974

Publisher :

Elsevier

Publication date :

2024-10-14

ISSN :

2468-1253

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Alcohol-associated hepatitis is characterised by jaundice and malaise in individuals with excessive and chronic alcohol intake, and is associated with high short-term mortality.1 Specific treatments for alcohol-associated ...
Show more >Alcohol-associated hepatitis is characterised by jaundice and malaise in individuals with excessive and chronic alcohol intake, and is associated with high short-term mortality.1 Specific treatments for alcohol-associated hepatitis are scarce, and treatment for the underlying alcohol use disorder (AUD) is often neglected in clinical practice.2 Management of severe alcohol-associated hepatitis is mainly based on supportive therapy, including nutrition and treating infections as they arise. Corticosteroids have been used to treat alcohol-associated hepatitis since the 1970s and remain the only effective treatment, although multiple studies show inadequate efficacy.1 Early liver transplantation has emerged as a novel strategy to improve survival in severe alcohol-associated hepatitis,3 yet access is not universally available.4 Little is known about international practice variations in managing alcohol-associated hepatitis. We aimed to examine practice patterns regarding the treatment of alcohol-associated hepatitis and adherence to current clinical guidelines and evidence.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2025-01-01T22:04:42Z
2025-01-15T09:00:28Z