Lifelong Voluntary Exercise Modulates ...
Type de document :
Article dans une revue scientifique
DOI :
PMID :
URL permanente :
Titre :
Lifelong Voluntary Exercise Modulates Age-Related Changes in Oxidative Stress
Auteur(s) :
Bouzid, Mohamed Amine [Auteur]
Activité Physique, Muscle, Santé [EA4488]
Filaire, Edith [Auteur]
Complexité, Innovation, Activités Motrices et Sportives [CIAMS]
Matran, Regis [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Robin, Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Fabre, Claudine [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Activité Physique, Muscle, Santé [EA4488]
Filaire, Edith [Auteur]
Complexité, Innovation, Activités Motrices et Sportives [CIAMS]
Matran, Regis [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Robin, Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Fabre, Claudine [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Titre de la revue :
International Journal of Sports Medicine
Nom court de la revue :
Int. J. Sports Med.
Numéro :
39
Pagination :
21-28
Éditeur :
Thieme
Date de publication :
2018-01-01
ISSN :
0172-4622
Mot(s)-clé(s) en anglais :
aging
exercise
physical activity
oxidative stress
exercise
physical activity
oxidative stress
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
The hypothesis that aging and regular physical activity could influence oxidative stress has been studied by comparing antioxidant activities (superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase ...
Lire la suite >The hypothesis that aging and regular physical activity could influence oxidative stress has been studied by comparing antioxidant activities (superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase (GR), ascorbic acid and α-Tocopherol) and malondialdehyde level (MDA) in four groups: young sedentary (n=15; age: 20.3±2.8 years; YS), young active (n=16; age: 21.4±1.9 years; YA), old sedentary (n=15; age: 65.1±3.5 years; OS) and old active (n=17; age: 67.2±4.8 years; OA). Antioxidant activities and MDA level were assessed at rest and after an incremental exercise. There was no difference in resting antioxidant activities and lipid peroxidation between YS and OS. However, resting SOD and GR activities were higher in YA compared to OA (p<0.01 and p<0.05, respectively) and resting MDA level was higher in OA compared to YA (p<0.01). After exercise, a significant increase in SOD and GPX activities was observed in YS, YA and OA (p<0.01). Likewise, after exercise a significant increase of MDA level in YA, OS and OA (p<0.01) was observed. In addition, the comparison of YA to OA and YS to OA revealed similar antioxidant activities and lipid peroxidation between YS and OA, whereas antioxidant activities were higher in YA compared to OA. These data suggest that beneficial effects of regular physical activity in antioxidant defense and lipid peroxidation damage could be impaired by the aging process and that regular physical activity in older adults could maintain age-related decreases in antioxidant defense.Lire moins >
Lire la suite >The hypothesis that aging and regular physical activity could influence oxidative stress has been studied by comparing antioxidant activities (superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase (GR), ascorbic acid and α-Tocopherol) and malondialdehyde level (MDA) in four groups: young sedentary (n=15; age: 20.3±2.8 years; YS), young active (n=16; age: 21.4±1.9 years; YA), old sedentary (n=15; age: 65.1±3.5 years; OS) and old active (n=17; age: 67.2±4.8 years; OA). Antioxidant activities and MDA level were assessed at rest and after an incremental exercise. There was no difference in resting antioxidant activities and lipid peroxidation between YS and OS. However, resting SOD and GR activities were higher in YA compared to OA (p<0.01 and p<0.05, respectively) and resting MDA level was higher in OA compared to YA (p<0.01). After exercise, a significant increase in SOD and GPX activities was observed in YS, YA and OA (p<0.01). Likewise, after exercise a significant increase of MDA level in YA, OS and OA (p<0.01) was observed. In addition, the comparison of YA to OA and YS to OA revealed similar antioxidant activities and lipid peroxidation between YS and OA, whereas antioxidant activities were higher in YA compared to OA. These data suggest that beneficial effects of regular physical activity in antioxidant defense and lipid peroxidation damage could be impaired by the aging process and that regular physical activity in older adults could maintain age-related decreases in antioxidant defense.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille
Institut Pasteur de Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille
Institut Pasteur de Lille
Collections :
Équipe(s) de recherche :
Activité Physique, Muscle, Santé (APMS)
Date de dépôt :
2019-09-24T07:28:01Z
2022-04-27T10:54:16Z
2024-02-07T07:01:45Z
2022-04-27T10:54:16Z
2024-02-07T07:01:45Z
Fichiers
- Bouzid et al..pdf
- Version éditeur
- Accès libre
- Accéder au document