Evaluation of single-extraction methods ...
Document type :
Article dans une revue scientifique: Article original
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Title :
Evaluation of single-extraction methods to estimate the oral bioaccessibility of metal(loid)s in soils
Author(s) :
Pelfrene, Aurélie [Auteur correspondant]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Sahmer, Karin [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Waterlot, Christophe [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Glorennec, Philippe [Auteur]
Institut de recherche en santé, environnement et travail [Irset]
Département Santé Environnement Travail et Génie Sanitaire [DSETGS]
Douay, Francis [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Le Bot, Barbara [Auteur]
Laboratoire d'étude et de recherche en environnement et santé [LERES]
Institut de recherche en santé, environnement et travail [Irset]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Sahmer, Karin [Auteur]

Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Waterlot, Christophe [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Glorennec, Philippe [Auteur]
Institut de recherche en santé, environnement et travail [Irset]
Département Santé Environnement Travail et Génie Sanitaire [DSETGS]
Douay, Francis [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Le Bot, Barbara [Auteur]
Laboratoire d'étude et de recherche en environnement et santé [LERES]
Institut de recherche en santé, environnement et travail [Irset]
Journal title :
Science of the Total Environment
Pages :
138553
Publisher :
Elsevier
Publication date :
2020-04
ISSN :
0048-9697
English keyword(s) :
Soil pollution
Human exposure
Single-extraction method
Metalloid
Metal
Human exposure
Single-extraction method
Metalloid
Metal
HAL domain(s) :
Sciences du Vivant [q-bio]/Santé publique et épidémiologie
English abstract : [en]
Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s ...
Show more >Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s determined via in vitro digestion methods. However, some validated methods are complex and costly, involving high technical skills and numerous reagents. The objective of the present study was to evaluate the suitability of four simple chemical extractions to mimic the bioaccessible fraction of As, Cd, and Pb in the gastric (G) and gastrointestinal (GI) phases obtained using the validated UBM (unified bioaccessibility method) test. Acetic acid (0.11 M), citric acid (0.11 M), EDTA (0.16 M), and hydrochloric acid (HCl, 0.65%) were separately tested in 201 soil samples with a wide range of physicochemical parameters and metal(loid)s concentrations. Significant linear relationships were observed with HCl, EDTA, and to a lesser extent with citric acid. For the cheaper HCl method, correlations with the UBM ranged from 0.91 to 0.99 for the G phase and from 0.72 to 0.97 for the GI phase. This test can be used at least as a first-tier screening to assess the oral bioaccessibility of As, Cd, and Pb.Show less >
Show more >Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s determined via in vitro digestion methods. However, some validated methods are complex and costly, involving high technical skills and numerous reagents. The objective of the present study was to evaluate the suitability of four simple chemical extractions to mimic the bioaccessible fraction of As, Cd, and Pb in the gastric (G) and gastrointestinal (GI) phases obtained using the validated UBM (unified bioaccessibility method) test. Acetic acid (0.11 M), citric acid (0.11 M), EDTA (0.16 M), and hydrochloric acid (HCl, 0.65%) were separately tested in 201 soil samples with a wide range of physicochemical parameters and metal(loid)s concentrations. Significant linear relationships were observed with HCl, EDTA, and to a lesser extent with citric acid. For the cheaper HCl method, correlations with the UBM ranged from 0.91 to 0.99 for the G phase and from 0.72 to 0.97 for the GI phase. This test can be used at least as a first-tier screening to assess the oral bioaccessibility of As, Cd, and Pb.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Source :
Submission date :
2025-02-26T12:51:25Z
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