Animal models of binge drinking, current ...
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
Permalink :
Title :
Animal models of binge drinking, current challenges to improve face validity
Author(s) :
Jeanblanc, Jerome [Auteur]
Rolland, Benjamin [Auteur]
Gierski, Fabien [Auteur]
Martinetti, Margaret P. [Auteur]
Naassila, Mickael [Auteur]
Rolland, Benjamin [Auteur]
Gierski, Fabien [Auteur]
Martinetti, Margaret P. [Auteur]
Naassila, Mickael [Auteur]
Journal title :
Neuroscience and biobehavioral reviews
Abbreviated title :
Neurosci Biobehav Rev
Publication date :
2018-05-05
ISSN :
1873-7528
English keyword(s) :
Binge drinking
Alcohol
Validity
Rodents
Animal models
Alcohol
Validity
Rodents
Animal models
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Binge drinking (BD), i.e., consuming a large amount of alcohol in a short period of time, is an increasing public health issue. Though no clear definition has been adopted worldwide the speed of drinking seems to be a ...
Show more >Binge drinking (BD), i.e., consuming a large amount of alcohol in a short period of time, is an increasing public health issue. Though no clear definition has been adopted worldwide the speed of drinking seems to be a keystone of this behavior. Developing relevant animal models of BD is a priority for gaining a better characterization of the neurobiological and psychobiological mechanisms underlying this dangerous and harmful behavior. Until recently, preclinical research on BD has been conducted mostly using forced administration of alcohol, but more recent studies used scheduled access to alcohol, to model more voluntary excessive intakes, and to achieve signs of intoxications that mimic the human behavior. The main challenges for future research are discussed regarding the need of good face validity, construct validity and predictive validity of animal models of BD.Show less >
Show more >Binge drinking (BD), i.e., consuming a large amount of alcohol in a short period of time, is an increasing public health issue. Though no clear definition has been adopted worldwide the speed of drinking seems to be a keystone of this behavior. Developing relevant animal models of BD is a priority for gaining a better characterization of the neurobiological and psychobiological mechanisms underlying this dangerous and harmful behavior. Until recently, preclinical research on BD has been conducted mostly using forced administration of alcohol, but more recent studies used scheduled access to alcohol, to model more voluntary excessive intakes, and to achieve signs of intoxications that mimic the human behavior. The main challenges for future research are discussed regarding the need of good face validity, construct validity and predictive validity of animal models of BD.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Research team(s) :
Troubles cognitifs dégénératifs et vasculaires
Submission date :
2019-11-27T13:03:33Z