Title :

Psychogenic non-epileptic seizures treated with guided transcranial direct current stimulation: a case report

Author(s) :

Leroy, Arnaud [Auteur]
415060|||Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Beigne, Martin [Auteur]
Service de Psychiatrie [CHRU Lille]
Petyt, Gregory [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Derambure, Philippe [Auteur]
531394|||Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 [M2SV]
Vaiva, Guillaume [Auteur]
415060|||Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Amad, Ali [Auteur]
415060|||Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]

Journal title :

Brain stimulation

Abbreviated title :

Brain Stimul

Volume number :

12

Pages :

794-796

Publication date :

2019-01-31

ISSN :

1876-4754

English keyword(s) :

Psychogenic non-epileptic seizure
tDCS
Trauma
Somatoform disorder
Dissociation
PET-Scan

HAL domain(s) :

Sciences du Vivant [q-bio]
Sciences cognitives

English abstract : [en]

Psychogenic non-epileptic seizures (PNES) are paroxysms of either altered subjective or objective manifestations that may mimic epileptic seizures (ES), without abnormal neuronal epileptiform activity. In this report, we ...
Show more >Psychogenic non-epileptic seizures (PNES) are paroxysms of either altered subjective or objective manifestations that may mimic epileptic seizures (ES), without abnormal neuronal epileptiform activity. In this report, we present the case of a 39-year-old woman with PNES and functional movement disorders, who was successfully treated with neuro-guided transcranial direct current stimulation (tDCS). We used a PET-guided tDCS approach, as a hypometabolism of the frontal region was revealed by FDG TEP scan. TDCs was performed 5 days/week, 2 times/day, during 3 weeks. All clinical manifestations were reported in a seizure diary. We also assessed dissociation, depression, alexithymia, psychotraumatic scales, and involuntary movements. The treatment was followed by a decrease of both psychogenic involuntary movements and PNES at 5 weeks. At the same time, PTSD symptoms, dissociative symptoms, depression and alexithymia improved. PET-scan and tDCS seems to be promising tools for the evaluation and treatment of PNES in clinical practice, and may have a specific role on dissociative symptoms.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172
• Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T13:04:30Z
2020-04-07T09:12:58Z
2023-06-05T11:29:42Z