Microangiopathy underlying mixed-location ...
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Microangiopathy underlying mixed-location intracerebral hemorrhages/microbleeds a pib-pet study
Author(s) :
Tsai, Hsin-Hsi [Auteur]
Pasi, Marco [Auteur]
Tsai, Li-Kai [Auteur]
Chen, Ya-Fang [Auteur]
Lee, Bo-Ching [Auteur]
Tang, Sung-Chun [Auteur]
Fotiadis, Panagiotis [Auteur]
Huang, Chen-Yu [Auteur]
Yen, Ruoh-Fang [Auteur]
Jeng, Jiann-Shing [Auteur]
Gurol, Mahmut Edip [Auteur]
Pasi, Marco [Auteur]
Tsai, Li-Kai [Auteur]
Chen, Ya-Fang [Auteur]
Lee, Bo-Ching [Auteur]
Tang, Sung-Chun [Auteur]
Fotiadis, Panagiotis [Auteur]
Huang, Chen-Yu [Auteur]
Yen, Ruoh-Fang [Auteur]
Jeng, Jiann-Shing [Auteur]
Gurol, Mahmut Edip [Auteur]
Journal title :
Neurology
Abbreviated title :
Neurology
Volume number :
92
Pages :
E774-E781
Publication date :
2019-02-19
ISSN :
0028-3878
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
To test the hypothesis that patients with concomitant lobar and deep intracerebral hemorrhages/microbleeds (mixed ICH) have predominantly hypertensive small vessel disease (HTN-SVD) rather than cerebral amyloid angiopathy ...
Show more >To test the hypothesis that patients with concomitant lobar and deep intracerebral hemorrhages/microbleeds (mixed ICH) have predominantly hypertensive small vessel disease (HTN-SVD) rather than cerebral amyloid angiopathy (CAA), using in vivo amyloid imaging. Eighty Asian patients with primary ICH without dementia were included in this cross-sectional study. All patients underwent brain MRI and 11 Patients with mixed ICH were younger (62.8 ± 11.7 vs 73.3 ± 11.9 years in CAA, ppppppp Patients with mixed ICH have much lower amyloid load than patients with CAA-ICH, while being similar to HTN-ICH. Overall, mixed ICH is probably caused by HTN-SVD, an important finding with clinical relevance.Show less >
Show more >To test the hypothesis that patients with concomitant lobar and deep intracerebral hemorrhages/microbleeds (mixed ICH) have predominantly hypertensive small vessel disease (HTN-SVD) rather than cerebral amyloid angiopathy (CAA), using in vivo amyloid imaging. Eighty Asian patients with primary ICH without dementia were included in this cross-sectional study. All patients underwent brain MRI and 11 Patients with mixed ICH were younger (62.8 ± 11.7 vs 73.3 ± 11.9 years in CAA, ppppppp Patients with mixed ICH have much lower amyloid load than patients with CAA-ICH, while being similar to HTN-ICH. Overall, mixed ICH is probably caused by HTN-SVD, an important finding with clinical relevance.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Research team(s) :
Troubles cognitifs dégénératifs et vasculaires
Submission date :
2019-11-27T13:37:03Z