Simulating bacterial transcription and ...
Document type :
Article dans une revue scientifique: Article original
Title :
Simulating bacterial transcription and translation in a stochastic pi-calculus
Author(s) :
Kuttler, Celine [Auteur]
Programming Languages for Biological Modeling and Simulation [BioComputing]
Laboratoire d'Informatique Fondamentale de Lille [LIFL]
Institut de Recherche Interdisciplinaire [Villeneuve d'Ascq] [IRI]

Programming Languages for Biological Modeling and Simulation [BioComputing]
Laboratoire d'Informatique Fondamentale de Lille [LIFL]
Institut de Recherche Interdisciplinaire [Villeneuve d'Ascq] [IRI]
Journal title :
Transactions on Computational Systems Biology
Pages :
113-149
Publisher :
Springer
Publication date :
2006
HAL domain(s) :
Informatique [cs]/Modélisation et simulation
English abstract : [en]
Stochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. ...
Show more >Stochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. transcription and translation, at the prototypical instance of bacteria. We reach extensibility through object-oriented abstractions, that are expressible in a stochastic π-calculus with pattern guarded inputs. We illustrate our generic model by simulating the effect of translational bursting in bacterial gene expression.Show less >
Show more >Stochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. transcription and translation, at the prototypical instance of bacteria. We reach extensibility through object-oriented abstractions, that are expressible in a stochastic π-calculus with pattern guarded inputs. We illustrate our generic model by simulating the effect of translational bursting in bacterial gene expression.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Collections :
Source :
Files
- https://hal.archives-ouvertes.fr/hal-00460081/document
- Open access
- Access the document
- https://hal.archives-ouvertes.fr/hal-00460081/document
- Open access
- Access the document
- document
- Open access
- Access the document
- bactExpression.pdf
- Open access
- Access the document
- document
- Open access
- Access the document
- bactExpression.pdf
- Open access
- Access the document