Nuclear medicine for photodynamic therapy ...
Type de document :
Compte-rendu et recension critique d'ouvrage
PMID :
Titre :
Nuclear medicine for photodynamic therapy in cancer: planning, monitoring and nuclear PDT
Auteur(s) :
Kharroubi Lakouas, Dris [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Huglo, Damien [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Mordon, Serge [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Vermandel, Maximilien [Auteur correspondant]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Huglo, Damien [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Mordon, Serge [Auteur]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Vermandel, Maximilien [Auteur correspondant]
Thérapies Laser Assistées par l'Image pour l'Oncologie - U 1189 [ONCO-THAI]
Titre de la revue :
Photodiagnosis and Photodynamic Therapy
Pagination :
Epub ahead of print
Éditeur :
Elsevier
Date de publication :
2017
ISSN :
1572-1000
Mot(s)-clé(s) en anglais :
Photodynamic therapy
Oncology
PET
SPECT
5-Aminolevulinic acid
PPIX
Oncology
PET
SPECT
5-Aminolevulinic acid
PPIX
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Ingénierie biomédicale/Médecine nucléaire
Sciences du Vivant [q-bio]/Cancer
Sciences du Vivant [q-bio]/Ingénierie biomédicale
Sciences du Vivant [q-bio]/Cancer
Sciences du Vivant [q-bio]/Ingénierie biomédicale
Résumé en anglais : [en]
Photodynamic therapy (PDT) is a modality with promising results for the treatment of various cancers. PDT is increasingly included in the standard of care for different pathologies. This therapy relies on the effects of ...
Lire la suite >Photodynamic therapy (PDT) is a modality with promising results for the treatment of various cancers. PDT is increasingly included in the standard of care for different pathologies. This therapy relies on the effects of light delivered to photosensitized cells. At different stages of delivery, PDT requires imaging toplan, evaluate and monitor treatment. The contribution of molecular imaging in this context is important and continues to increase. In this article, we review the contribution of nuclear medicine imaging in oncology to PDT for planning and therapeutic monitoring purposes. Several solutions have been proposed to plan PDT from nuclear medicine imaging. For instance, photosensitizer biodistribution has been evaluated with aradiolabeled photosensitizer or with conventionalradiopharmaceuticals on positron emission tomography. The effects of PDT delivery have also been explored with specific SPECT or PET radiopharmaceuticals to evaluate the effects on cells (apoptosis, necrosis, proliferation, metabolism) or vascular damage. Finally, the synergy between photosensitizers and radiopharmaceuticals has been studied considering the Cerenkov effect to activate photosensitized cells.Lire moins >
Lire la suite >Photodynamic therapy (PDT) is a modality with promising results for the treatment of various cancers. PDT is increasingly included in the standard of care for different pathologies. This therapy relies on the effects of light delivered to photosensitized cells. At different stages of delivery, PDT requires imaging toplan, evaluate and monitor treatment. The contribution of molecular imaging in this context is important and continues to increase. In this article, we review the contribution of nuclear medicine imaging in oncology to PDT for planning and therapeutic monitoring purposes. Several solutions have been proposed to plan PDT from nuclear medicine imaging. For instance, photosensitizer biodistribution has been evaluated with aradiolabeled photosensitizer or with conventionalradiopharmaceuticals on positron emission tomography. The effects of PDT delivery have also been explored with specific SPECT or PET radiopharmaceuticals to evaluate the effects on cells (apoptosis, necrosis, proliferation, metabolism) or vascular damage. Finally, the synergy between photosensitizers and radiopharmaceuticals has been studied considering the Cerenkov effect to activate photosensitized cells.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Source :
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