Title :

Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP) – September 2015

Author(s) :

Albaladejo, Pierre [Auteur]
Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 [TIMC-IMAG]
Centre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
Bonhomme, Fanny [Auteur]
Blais, Normand [Auteur]
Collet, Jean-Philippe [Auteur]
Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie [UPMC]
Institut de cardiologie [CHU Pitié-Salpêtrière]
Faraoni, David [Auteur]
Fontana, Pierre [Auteur]
Godier, Anne [Auteur]
Fondation Ophtalmologique Adolphe de Rothschild [Paris]
Llau, Juan [Auteur]
Longrois, Dan [Auteur]
Laboratoire de Recherche Vasculaire Translationnelle [LVTS (UMR_S_1148 / U1148)]
Service d'anesthésie - réanimation chirurgicale [CHU Bichat]
Marret, Emmanuel [Auteur]
Mismetti, Patrick [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Rosencher, Nadia [Auteur]
Hôpital Hôtel-Dieu [Paris]
Hôpital Cochin [AP-HP]
Roullet, Stéphanie [Auteur]
Hôpital Hôtel-Dieu [Paris]
Hôpital Cochin [AP-HP]
Samama, Charles-Marc [Auteur]
Service Anesthésie - Réanimation [Bordeaux]
Schved, Jean-François [Auteur]
Département d'Hématologie biologique [Saint-Eloi - CHU Montpellier]
Sie, Pierre [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Steib, Annick [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Susen, Sophie [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Perioperative Hemostasis (gihp), French Working Group On [Auteur]

Journal title :

Anaesthesia Critical Care & Pain Medicine

Pages :

73 - 76

Publisher :

Elsevier Masson

Publication date :

2017-02

ISSN :

2352-5568

English keyword(s) :

Direct oral anticoagulants
Elective surgery
Periprocedural management

HAL domain(s) :

Sciences du Vivant [q-bio]/Médecine humaine et pathologie

English abstract : [en]

Since 2011, data on patients exposed to direct oral anticoagulants (DOAs) while undergoing invasive procedures have accumulated. At the same time, an increased hemorrhagic risk during perioperative bridging anticoagulation ...
Show more >Since 2011, data on patients exposed to direct oral anticoagulants (DOAs) while undergoing invasive procedures have accumulated. At the same time, an increased hemorrhagic risk during perioperative bridging anticoagulation without thrombotic risk reduction has been demonstrated. This has led the GIHP to update their guidelines published in 2011. For scheduled procedures at low bleeding risk, it is suggested that patients interrupt DOAs the night before irrespective of type of drug and to resume therapy six hours or more after the end of the invasive procedure. For invasive procedures at high bleeding risk, it is suggested to interrupt rivaroxaban, apixaban and edoxaban three days before. Dabigatran should be interrupted according to the renal function, four days and five days if creatinine clearance is higher than 50mL/min and between 30 and 50mL/min, respectively. For invasive procedures at very high bleeding risk such as intracranial neurosurgery or neuraxial anesthesia, longer interruption times are suggested. Finally, bridging with parenteral anticoagulation and measurement of DOA concentrations can no longer routinely be used.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011

Source :

Harvested from HAL