Titre :

Alginate versus npwt in the preparation of surgical excisions for an stsg: atec trial

Auteur(s) :

Casanova, Dominique [Auteur]
Hôpital de la Conception [CHU - APHM] [LA CONCEPTION]
Guerreschi, Pierre [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Advanced Drug Delivery Systems (ADDS) - U1008
Sinna, Raphael [Auteur]
CHU Amiens-Picardie
Bertheuil, Nicolas [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Philandrianos, Cecile [Auteur]
Hôpital de la Conception [CHU - APHM] [LA CONCEPTION]
Chignon-Sicard, Berengere [Auteur]
Université Côte d'Azur [UniCA]
Duteille, Franck [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Atlan, Michael [Auteur]
CHU Tenon [AP-HP]
Rousseau, Pascal [Auteur]
Centre Hospitalier Universitaire d'Angers [CHU Angers]
Chatellier, Gilles [Auteur]
CIC - HEGP [CIC 1418]
Boucher, Fabien [Auteur]
Pham Dang, Nathalie [Auteur]
CHU Clermont-Ferrand
Cambon-Binder, Adeline [Auteur]
CHU Saint-Antoine [AP-HP]
Michot, Audrey [Auteur]
Pluvy, Isabelle [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Seigle-Murandi, Frederic [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Hu, Weiguo [Auteur]
Centre Hospitalier Régional Universitaire de Brest [CHRU Brest]
Revol, Marc [Auteur]
CHU Tenon [AP-HP]

Titre de la revue :

Plastic and Reconstructive Surgery, Global Open

Nom court de la revue :

Plast Reconstr Surg Glob Open

Numéro :

8

Pagination :

e2691

Date de publication :

2020-03-01

ISSN :

2169-7574

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

A calcium alginate dressing (ALGINATE) and negative pressure wound therapy (NPWT) are frequently used to treat wounds which heal by secondary intention. This trial compared the healing efficacy and safety of these 2 ...
Lire la suite >A calcium alginate dressing (ALGINATE) and negative pressure wound therapy (NPWT) are frequently used to treat wounds which heal by secondary intention. This trial compared the healing efficacy and safety of these 2 treatments. This randomized, non-inferiority trial enrolled patients who underwent skin excision (>30 cm2 ALGINATE and NPWT were applied to 47 and 48 patients, respectively. The mean time to optimal granulation was 19.98 days (95% CI, 17.7-22.3) with ALGINATE and 20.54 (95% CI, 17.6-23.5) with NPWT. Between group difference was -0.56 days (95% CI -4.22 to 3.10). The non-inferiority of ALGINATE versus NPWT was demonstrated. No AE related to the treatment occurred with ALGINATE versus 14 AEs with NPWT. There was no difference in the impact of the treatments on the patient's daily life. This trial demonstrates that ALGINATE has a similar healing efficacy to that of NPWT and that is markedly better with regard to patient safety.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Date de dépôt :

2021-01-20T15:58:57Z
2024-02-23T08:53:54Z