Title :

Prospective multicentric follow-up study of cochlear implantation in adults with single-sided deafness: tinnitus and audiological outcomes

Author(s) :

Poncet-Wallet, Christine [Auteur]
Fondation Ophtalmologique Adolphe de Rotschild
Mamelle, Elisabeth [Auteur]
Fondation Ophtalmologique Adolphe de Rotschild
Godey, Benoit [Auteur]
Université de Rennes - Faculté de Médecine [UR Médecine]
Truy, Eric [Auteur]
Hôpital Edouard Herriot [CHU - HCL]
Guevara, Nicolas [Auteur]
Université Côte d'Azur [UniCA]
Ardoint, Marine [Auteur]
Oticon Medical / Neurelec
Gnansia, Dan [Auteur]
Oticon Medical / Neurelec
Hoen, Michel [Auteur]
Oticon Medical / Neurelec
Saai, Sonia [Auteur]
Oticon Medical / Neurelec
Mosnier, Isabelle [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Lescanne, Emmanuel [Auteur]
Hôpital Bretonneau
Bakhos, David [Auteur]
Hôpital Bretonneau
Université de Tours [UT]
Vincent, Christophe [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]

Journal title :

Otology and Neurotology

Abbreviated title :

Otol. Neurotol.

Volume number :

41

Pages :

458-466

Publication date :

2020-04-01

ISSN :

1537-4505

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

OBJECTIVE: This study investigated the audiological and tinnitus outcomes of cochlear implantation (CI) in adults with single-sided deafness (SSD) and tinnitus. METHODS: Multicentered prospective, non-randomized intervention ...
Show more >OBJECTIVE: This study investigated the audiological and tinnitus outcomes of cochlear implantation (CI) in adults with single-sided deafness (SSD) and tinnitus. METHODS: Multicentered prospective, non-randomized intervention study. METHODS: Six French CI centers. METHODS: Twenty-six patients with SSD and incapacitating tinnitus (Tinnitus Handicap Inventory [THI] >58) underwent cochlear implantation. METHODS: First, CIs delivered only masking white noise stimulation for 1 month and then standard CI stimulation. METHODS: Before and after CI surgery, patients completed the THI, Tinnitus Reaction Questionnaire (TRQ), Subjective Tinnitus Severity Scale (STSS), and two visual analogue scales quantifying tinnitus loudness and annoyance. Speech perception in spatialized noise was tested at 13 months. RESULTS: The first month of white noise stimulation triggered a significant improvement in THI scores (72 ± 9 to 55 ± 20, p < 0.05). No change was observed for the other measures. After 1 year of standard CI stimulation, 23 patients (92%) reported a significant improvement in tinnitus. This improvement started 1 to 2 months after CI and exceeded 40% improvement for 14 patients (54%). Average speech-in-noise perception after 1 year significantly improved for the 23 patients who completed these measures. CONCLUSIONS: CI is efficacious to reduce the handicap of patient with SSD and incapacitating tinnitus, leading to a decrease in reported tinnitus and partial restoration of binaural hearing abilities.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Submission date :

2021-01-20T15:59:00Z
2024-02-16T13:46:13Z