Title :

Nouvelle stratégie chirurgicale dans les mastectomies bilatérales prophylactiques avec reconstruction par prothèses chez les patientes présentant une mutation du gène BRCA

Translated title :

New surgical strategy in breast reconstruction with implants for bilateral prophylactic mastectomies with BRCA gene mutation

Author(s) :

Deveaux, Cesar [Auteur]
Hôpital Roger Salengro [Lille]
Calibre, Clotilde [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Duquennoy- Martinot, Veronique [Auteur]
Maladies RAres du DEveloppement embryonnaire et du MEtabolisme : du Phénotype au Génotype et à la Fonction - ULR 7364 [RADEME]
Maladies Rares du Développement : Génétique, Régulation et Protéomique (RADEME) - ULR 7364
Guerreschi, Pierre [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Advanced Drug Delivery Systems (ADDS) - U1008
Dumont, A. [Auteur]
Centre Hospitalier Boulogne-sur-mer

Journal title :

Annales de chirurgie plastique et esthétique

Abbreviated title :

Ann Chir Plast Esthet

Volume number :

65

Pages :

284-293

Publication date :

2020-05-29

ISSN :

1768-319X

English keyword(s) :

Breast reconstruction
BRCA
Prophylactic mastectomy
Breast implants

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

BACKGROUND: For the past decades, number of prophylactic bilateral mastectomies using reconstruction with implants increases. We describe a new surgical strategy and analyse its safety and feasability. METHODS: It is a ...
Show more >BACKGROUND: For the past decades, number of prophylactic bilateral mastectomies using reconstruction with implants increases. We describe a new surgical strategy and analyse its safety and feasability. METHODS: It is a retrospective, descriptive and monocentric study. The first step of surgery consisted in obteining a peri-prosthetic capsule with implants and if there was a mammary hypertrophy and/or ptosis, it was corrected at the same time. The second step of surgery was the nipple-sparing mastectomy with change of implants for bigger ones. Third step consisted in a lipofilling. RESULTS: Seven patients were included. 6 women had a BRCA1 gene mutation. Mean age was 35.6 year-old [29.6; 41.6], mean BMI was 23.8kg/m2 CONCLUSIONS: This new strategy could decrease complication rate, improve aesthetic outcome and decrease psychological impact of surgery.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008
• Maladies Rares du Développement : Génétique, Régulation et Protéomique (RADEME) - ULR 7364

Submission date :

2021-01-20T15:59:26Z
2024-02-20T08:21:22Z