Experimental evidence for circular inference in schizophrenia

Jardri, Renaud; Duverne, Sandrine; Litvinova, Alexandra S.; Denève, Sophie

Type de document :

Article dans une revue scientifique

DOI :

10.1038/ncomms14218

PMID :

28139642

URL permanente :

http://hdl.handle.net/20.500.12210/4007

Titre :

Experimental evidence for circular inference in schizophrenia

Auteur(s) :

Jardri, Renaud [Auteur]

Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Duverne, Sandrine [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Litvinova, Alexandra S. [Auteur]
Lomonosov Moscow State University = Université d'État Lomonossov de Moscou [Moscou] [MSU]
Denève, Sophie [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]

Titre de la revue :

Nature communications

Numéro :

Pagination :

14218

Date de publication :

2017-01-31

ISSN :

2041-1723

Discipline(s) HAL :

Sciences cognitives

Résumé en anglais : [en]

<p>Schizophrenia is a mental disorder characterized by hallucinations and delusions. Here Schizophrenia (SCZ) is a complex mental disorder that may result in some combination ofhallucinations, delusions and disorganized ...
Lire la suite ><p>Schizophrenia is a mental disorder characterized by hallucinations and delusions. Here Schizophrenia (SCZ) is a complex mental disorder that may result in some combination ofhallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls(CTLs) report their level of confidence on a forced-choice task that manipulated the strengthof sensory evidence and prior information. Neither group’s responses can be explained bysimple Bayesian inference. Rather, individual responses are best captured by a modelwith different degrees of circular inference. Circular inference refers to a corruption ofsensory data by prior information and vice versa, leading us to ‘see what we expect’(through descending loops), to ‘expect what we see’ (through ascending loops) or both.Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positivesymptoms. Descending loops correlate with the severity of negative symptoms. Both loopscorrelate with disorganized symptoms. The findings suggest that circular inference mightmediate the clinical manifestations of SCZ.Lire moins >

Langue :

Anglais

Audience :

Non spécifiée

Établissement(s) :

Université de Lille
CNRS
CHU Lille

Collections :

Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Équipe(s) de recherche :

Équipe Psychiatrie & Croyance (PsyCHIC)

Date de dépôt :

2019-02-13T14:17:58Z
2020-01-23T08:28:34Z
2020-03-23T14:21:40Z

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Ce document est diffusé sous licence Attribution 3.0 United States

Historique des modifications

Numéro de version	Lien	Date de modification
3	20.500.12210/4007*	2020-03-23T14:15:16Z
2	20.500.12210/4007.2	2020-01-23T08:27:42Z
1	20.500.12210/4007.1	2019-02-13T14:17:58Z

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