Title :

Similarity between remembering the past and imagining the future in Alzheimer's disease: Implication of episodic memory

Author(s) :

El Haj, Mohamad [Auteur]
Unité de Recherche en Sciences Cognitives et Affectives [URECA]
Antoine, Pascal [Auteur]
Unité de Recherche en Sciences Cognitives et Affectives [URECA]
Kapogiannis, Dimitrios [Auteur]

Journal title :

Neuropsychologia

Abbreviated title :

Neuropsychologia

Volume number :

66

Pages :

119-125

Publication date :

2014-11-20

ISSN :

1873-3514

English keyword(s) :

Alzheimer’s disease
Episodic memory
Future thinking
Imagination

HAL domain(s) :

Sciences cognitives

English abstract : [en]

Recent studies suggest that common cognitive processes and neuroanatomical substrates underlie the ability to remember the past and imagine the future. We studied these cognitive processes in patients with Alzheimer's ...
Show more >Recent studies suggest that common cognitive processes and neuroanatomical substrates underlie the ability to remember the past and imagine the future. We studied these cognitive processes in patients with Alzheimer's Disease (AD). We asked 27 participants with AD and 30 older controls, matched by age, sex, and educational level, to generate past and future autobiographical events. Autobiographical generation was analyzed with respect to theme, general autobiographical performance, contextual performance, self-defining memories, and autonoetic reliving/re-experiencing. Unlike older controls, most AD participants evoked similar themes when generating past and future events (n=23/30 participants). These participants also showed similar autobiographical and contextual performance, similar amount of self-defining memories, and similar autonoetic states when generating past and future events. Further, significant correlations were detected between hippocampal-dependent memory decline in AD participants and their ability to relive past and future events. These outcomes suggest striking similarities between remembering the past and imagining the future in AD. Due to their memory decline, imagining the future in AD patients is likely to draw heavily from the little amount of available information from past episodes, resulting in striking similarities between remembering the past and imagining the future. Finally, and unlike AD participants, older controls mentally "try out" alternative approaches to upcoming situations without replicating the same schemes of past events.Show less >

Language :

Anglais

Audience :

Non spécifiée

Administrative institution(s) :

Université de Lille
CNRS
CHU Lille

Collections :

• Autres travaux scientifiques

Submission date :

2019-02-13T14:48:30Z
2020-04-14T08:44:33Z
2020-04-17T08:57:27Z
2020-04-29T12:42:05Z