Title :

Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project.

Author(s) :

De Pascale, Gennaro [Auteur]
Ranzani Otavio, T [Auteur]
Nseir, Saad [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Chastre, Jean [Auteur]
Welte, Tobias [Auteur]
Antonelli, Massimo [Auteur]
Navalesi, Paolo [Auteur]
Garofalo, Eugenio [Auteur]
Bruni, Andrea [Auteur]
Coelho Luis, Miguel [Auteur]
Skoczynski, Szymon [Auteur]
Longhini, Federico [Auteur]
Taccone Fabio, Silvio [Auteur]
Grimaldi, David [Auteur]
Salzer Helmut J, F [Auteur]
Lange, Christoph [Auteur]
Froes, Filipe [Auteur]
Artigas, Antonio [Auteur]
Diaz, Emili [Auteur]
Valles, Jordi [Auteur]
Rodriguez, Alejandro [Auteur]
Panigada, Mauro [Auteur]
Comellini, Vittoria [Auteur]
Fasano, Luca [Auteur]
Soave Paolo, M [Auteur]
Spinazzola, Giorgia [Auteur]
Luyt, Charles-Edouard [Auteur]
Alvarez-Lerma, Francisco [Auteur]
Marin, Judith [Auteur]
Masclans Joan, Ramon [Auteur]
Chiumello, Davide [Auteur]
Pezzi, Angelo [Auteur]
Schultz, Marcus [Auteur]
Mohamed, Hafiz [Auteur]
Van Der Eerden, Menno [Auteur]
Hoek Roger A, S [Auteur]
Gommers D A M P, J [Auteur]
Pasquale Marta, Di [Auteur]
Civljak, Rok [Auteur]
Kutlesa, Marko [Auteur]
Bassetti, Matteo [Auteur]
Dimopoulos, George [Auteur]
Nava, Stefano [Auteur]
Rios, Fernando [Auteur]
Zampieri Fernando, G [Auteur]
Povoa, Pedro [Auteur]
Bos Lieuwe, D [Auteur]
Aliberti, Stefano [Auteur]
Torres, Antonio [Auteur]
Martin-Loeches, Ignacio [Auteur]

Journal title :

ERJ open research

Abbreviated title :

ERJ Open Res

Volume number :

3

Publication date :

2017-10-01

ISSN :

2312-0541
2312-0541

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A ...
Show more >The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI. This article describes the methodology of this study. A specific interest is the clinical impact of non-ICU-acquired nosocomial pneumonia requiring ICU admission, non-ventilator-associated LRTIs occurring in the ICU, and ventilator-associated tracheobronchitis. The clinical meaning of microbiologically negative infectious episodes and specific details on antibiotic administration modalities, dosages and duration are also highlighted. Recently released guidelines address many unresolved questions which might be answered by such large-scale observational investigations. In light of the paucity of data regarding such topics, new interesting information is expected to be obtained from our network research activities, contributing to optimisation of care for critically ill patients in the ICU.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Fungal associated invasive and inflammatory diseases

Submission date :

2019-03-01T14:09:30Z